The ratio between the percentage of specific cells (Tregs and Tconvs) in the ex vivo expansions and peripheral blood (n=10)
Ex vivo expansion versus peripheral blood | Percent of specific Tregs in all Tregs ex vivo (mean) | Percent of specific Tregs in all Tregs in peripheral blood (mean) | Ratio of Tregs Ex vivo/peripheral blood | Percent of specific Tconvs in all Tconvs ex vivo (mean) | Percent of specific Tconvs in all Tconvs in peripheral blood (mean) | Ratio of Tconvs Ex vivo/peripheral blood |
Proinsulin 73–90 | 4.97 | 0.48 | 10.37 | 2.51 | 0.22 | 11.38* |
Proinsulin 90–104 | 6.79 | 0.70 | 9.62 | 4.24 | 0.22 | 19.20* |
GAD65-555–567 | 0.80 | 0.22 | 3.58 | 0.65 | 0.22 | 2.95 |
GAD65-274–286 | 1.20 | 0.18 | 6.34 | 1.06 | 0.08 | 12.86* |
*Expansions in which the dynamics of Tconv proliferation was higher than that of Tregs.