Table 3

Age-specific and sex-specific incidence and adjusted HR of colorectal cancer in relation to CHMs use in patients with type 2 diabetes

Variables	CHMs non-users			CHMs users			Crude HR (95% CI)	Adjusted HR (95% CI)
Variables	Case	PYs	Incidence	Case	PYs	Incidence	Crude HR (95% CI)	Adjusted HR (95% CI)
Female
≤50 years	33	26 100.8	1.26	17	26 277.02	0.65	0.50 (0.28 to 0.90)	0.50 (0.27 to 0.89)*
>50 years	154	58 674.38	2.62	107	48 944.48	2.19	0.84 (0.66 to 1.07)	0.84 (0.65 to 1.07)*
All	187	84 775.18	2.21	124	75 221.5	1.65	0.76 (0.59 to 0.94)	0.76 (0.61 to 0.96)†
Male
≤50 years	39	25 323.32	1.54	20	22 241.56	0.90	0.60 (0.35 to 0.98)	0.59 (0.34 to 0.97)*
>50 years	149	41 646.54	3.58	91	37 788.8	2.41	0.67 (0.52 to 0.87)	0.68 (0.52 to 0.88)*
All	188	66 969.86	2.81	111	60 030.36	1.85	0.65 (0.52 to 0.83)	0.66 (0.53 to 0.84)†

Incidence rate is per 1000 PYs.
*Model adjusted for urbanization level, monthly income and comorbidity.
†Model adjusted for age, urbanization level, monthly income and comorbidity.
CHMs, Chinese herbal medicines; PYs, person-years.