Characteristics of patients with and without diabetes mellitus at baseline
| Diabetes (n=8236) | Non-diabetes (n=3856) | P value | |
| Mean age (years)±SD | 65.5±8.7 | 62.2±10.4 | <0.001 |
| Male sex (%) | 76 | 78 | 0.008 |
| Race (%) | <0.001 | ||
| White | 78 | 91 | |
| Black | 3.0 | 1.4 | |
| Asian | 13.4 | 5.0 | |
| Other | 5.3 | 2.7 | |
| Mean body mass index±SD | 31.1±5.9 | 28.3±4.7 | <0.001 |
| Index diagnosis (%) | |||
| Recent ACS 30–365 days | 16 | 61 | <0.001 |
| Cerebrovascular disease | 21 | 25 | <0.001 |
| Peripheral arterial disease | 17 | 26 | <0.001 |
| CAD | 93 | 83 | <0.001 |
| Cardiovascular risk factors (%) | |||
| Hypertension | 92 | 78 | <0.001 |
| Current smoker | 14 | 20 | <0.001 |
| Prior myocardial infarction | 60 | 83 | <0.001 |
| Prior PCI | 71 | 74 | 0.001 |
| Prior CABG | 33 | 20 | <0.001 |
| Prior heart failure | 15 | 11 | <0.001 |
| COPD | 11 | 10 | 0.08 |
| Renal impairment | 11 | 5 | <0.001 |
| Lipids (mg/dL) | |||
| Mean LDL cholesterol | 80±27 | 84±29 | <0.001 |
| Mean HDL cholesterol | 44±11 | 48±12 | <0.001 |
| Median triglyceride (IQR) | 136 (99, 187) | 113 (85, 158) | <0.001 |
| Mean apolipoprotein A1 | 137±25 | 142±26 | <0.001 |
| Mean apolipoprotein B | 78±22 | 78±23 | <0.001 |
| Median lipoprotein(a) (IQR) | 27 (10, 99) | 32 (13, 125) | <0.001 |
| Median HS CRP (IQR) (mg/L) | 1.53 (0.75, 3.42) | 1.44 (0.71, 3.03) | 0.003 |
| Medications (%) | |||
| Any statin | 96 | 97 | 0.011 |
| High-intensity statin | 43 | 55 | <0.001 |
| ACEi/ARB | 80 | 72 | <0.001 |
| Aspirin | 84 | 81 | 0.002 |
ACEi, ACE inhibitor; ACS, acute coronary syndrome; ARB, angiotensin-receptor blocker; CABG, coronary artery bypass graft; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; HDL, high-density lipoprotein; HS CRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein; PCI, percutaneous coronary intervention.