Table 1

Summary of the included studies

StudySubjects (T/C)DurationInterventionTCM outcomeControlControl outcome
BMI/WCFBG/2hPG/HbA1cTC/TG/LDL/HDLSBP/DBPBMI/WCFBG/2hPGTC/TG/LDL/HDLSBP/DBP
Chen 201163/5912 monthsTianqi Jiangtang capsule+basic treatmentBMI: 26.80±2.61 WC: 94.11±5.99FBG: 6.12±0.72
2hPG: 8.28±0.27
TC: 5.03±0.93
TG: 1.64±1.10 (39)
LDL: 2.92±0.85
HDL:1.46±0.42 (38)
SBP: 127.73±9.19 DBP: 79.52±5.72Placebo+basic treatmentBMI: 26.50±2.25 WC: 93.68±6.42FBG: 6.63±0.96
2hPG: 9.18±2.44
TC: 4.93±1.06
TG: 1.69±0.60
LDL: 2.69±0.98
HDL: 1.51±0.63
SBP: 126.17±7.72 DBP: 78.41±6.93
Fan 201240/4012 weeksWuling powder+basic treatmentBMI: 23.61±1.37 WC: 83.50±3.80FBG: 4.85±0.96 2hPG: 10.61±3.54
HbA1c: 6.59±0.94
TC: 3.60±0.67
TG: 1.82±0.72
LDL: 1.73±0.63
HDL: 1.49±0.30
SBP: 128.50±3.72 DBP: 80.67±2.46Basic treatmentBMI: 24.37±1.32 WC: 86.12±8.24FBG: 5.08±0.69
2hPG: 11.04±2.34 HbA1c: 6.31±0.70
TC: 3.74±1.20
TG: 1.92±1.06
LDL: 2.18±0.74
HDL: 1.12±0.28
SBP: 138.33±4.64 DBP: 88.80±2.66
Huang 201930/3190 daysErchen combined with Taohong Siwu decoction+basic treatmentBMI: 27.23±3.13 WC: 92.78±9.04FBG: 5.43±1.57TC: 4.18±1.42
TG: 1.26±0.49
LDL: 2.64±0.81
HDL: 1.23±0.29
SBP: 123.61±8.50 DBP: 73.87±7.73Basic treatmentBMI: 27.08±4.60 WC: 92.72±7.13FBG: 6.30±1.67TC: 5.03±0.98
TG: 1.90±1.15
LDL: 2.77±0.78
HDL: 1.13±0.24
SBP: 121.4±10.69 DBP: 74.9±7.49
Lian 201283/8212 weeksYi Tang Kang+basic treatmentBMI: 26.60±2.81FBG: 5.82±0.52 2hPG: 7.33±1.65 HbA1c: 5.83±0.60TC: 4.92±0.99
TG: 1.68±0.66
LDL: 2.99±0.71
HDL: 1.29±0.31
SBP: 130.55±5.21 DBP: 81.65±3.77Placebo+basic treatmentBMI: 27.35±2.75FBG: 5.96±0.68
2hPG: 7.99±1.67
HbA1c: 6.04±0.63
TC: 5.38±1.89
TG: 1.74±0.84
LDL: 3.25±0.74
HDL: 1.34±0.70
SBP: 38.37±8.12 DBP: 86.69±5.20
Liu 201735/3512 weeksWenpi Fuzhen decoction+basic treatmentBMI: 26.41±3.25 WC: 89.50±8.22FBG: 5.72±1.33 2hPG: 7.24±1.87 HbA1c: 5.59±1.23TC: 4.67±1.12
TG: 2.08±0.81
LDL: 3.32±0.74
HDL: 1.23±0.46
SBP: 133.66±4.97 DBP: 83.01±5.43Placebo+basic treatmentBMI: 28.78±4.11 WC: 93.99±9.23FBG:6.36±1.21
2hPG:8.30±2.41
HbA1c:6.13±0.94
TC: 5.22±0.98
TG: 2.50±0.94
LDL: 3.81±0.88
HDL: 1.17±0.32
SBP: 139.84±6.28 DBP: 88.94±6.11
Wang 201286/8112 weeksJiangtang pill+basic treatmentBMI: 23.41±2.16FBG: 5.79±0.66 2hPG: 7.53±1.44 HbA1c: 5.89±0.69TC: 4.94±0.91
TG: 1.50±0.90
LDL: 3.06±0.67
HDL: 1.23±0.28
SBP: 134.26±8.07 DBP: 84.51±5.04Placebo+basic treatmentBMI:26.37±2.50FBG: 5.95±0.60
2hPG: 8.24±1.33
HbA1c: 5.98±0.86
TC: 5.05±0.82
TG: 1.80±1.00
LDL: 3.16±0.62
HDL: 1.27±0.27
SBP: 140.17±9.69 DBP: 88.84±5.57
Wang 201360/6012 weeksHeye Jiangzhi decoction+basic treatmentBMI: 25.53±1.28 WC: 88.5±3.64FBG: 6.61±0.95 2hPG: 10.46±3.24TC: 3.42±1.16
TG: 1.56±0.68
LDL: 1.88±0.72
HDL: 1.70±0.48
SBP: 132.29±9.87 DBP: 82.73±7.72Basic treatmentBMI: 26.27±2.03 WC: 88.68±7.53FBG: 6.98±1.37
2hPG: 11.14±2.04
TC: 4.08±0.93
TG: 2.02±1.11
LDL: 1.94±0.57
HDL: 1.56±0.46
SBP: 140.0±14.38 DBP: 86.9±7.56
Wang 201648/4812 weeksYiqi Huaju formula+basic treatmentBMI: 25.36±2.32 WC: 88.89±8.83 WHtR: 0.88±0.06FBG: 6.24±1.31 2hPG: 8.68±2.61 HbA1c: 7.04±1.25TC: 4.25±0.96
TG: 1.60±0.70
LDL: 2.55±0.70
HDL: 1.16±0.28
SBP: 125.50±5.83 DBP: 78.61±5.40Placebo+basic treatmentBMI: 27.66±2.21 WC: 97.10±11.00 WHtR: 0.94±0.05FBG: 7.06±2.08
2hPG: 10.66±3.24 HbA1c: 7.54±1.17
TC: 4.22±0.67
TG: 1.92±0.68
LDL: 2.58±0.52
HDL: 1.10±0.22
SBP: 130.00±9.03 DBP: 81.64±6.22
Yang 201340/2012 weeksHuayu Fuyuan capsule +basic treatmentWC: 118.40±11.27FBG: 6.31±0.85TG: 1.56±0.37
HDL: 1.52±0.38
SBP: 129.60±10.92 DBP: 79.40±7.70Basic treatmentWC: 117.43±9.42FBG: 6.70±1.09TG: 1.81±0.25
HDL: 1.41±0.39
SBP: 131.10±6.24 DBP: 78.70±6.78
Zhang 201436/3712 weeksSanhuang Danshen decoction+basic treatmentBMI: 24.96±1.64 WC: 90.17±6.72 WHtR: 0.55±0.04FBG: 5.56±2.11 2hPG: 7.47±3.20 HbA1c: 6.22±2.10TC: 4.18±0.80
TG: 1.64±0.45
LDL: 2.66±0.60
HDL: 1.38±0.33
Basic treatmentBMI: 24.85±1.70 WC: 91.84±6.43 WHtR: 0.55±0.04FBG: 5.81±0.74
2hPG: 7.84±3.33
HbA1c: 7.13±0.90
TC: 4.60±1.10
TG: 2.01±1.51
LDL: 2.75±0.91
HDL: 1.24±0.33
Zhang 201685/8412 weeksYangyin Jiangya capsule+Jiangzhuo Quyu granule+basic treatmentBMI: 23.8±3.1 WC: 88.6±7.2 WHtR: 0.89±0.05FBG: 5.40±0.55 2hPG: 7.59±0.68 HbA1c: 5.49±0.4TC: 4.91±0.67
TG: 1.37±0.21
LDL: 2.31±0.57
HDL: 1.45±0.25
SBP: 125.3±5.8 DBP: 78.2±4.8Basic treatmentBMI: 24.6±2.9 WC: 91.4±7.4 WHtR: 0.93±0.04FBG: 5.82±0.59
2hPG: 8.17±0.88
HbA1c: 5.85±0.57
TC: 5.06±0.68
TG: 1.58±0.23
LDL: 2.65±0.62
HDL: 1.25±0.28
SBP: 128.8±6.3 DBP: 82.6±5.3
Chen 201430/3012 weeksHeye Jiangzhi decoctionBMI: 25.03±1.57 WC: 87.87±3.47FBG: 6.42±0.68 2hPG: 7.50±0.72TC: 3.71±0.64
TG: 2.13±0.46
LDL: 2.37±0.27
HDL: 1.13±0.10
SBP: 134.63±4.36 DBP: 83.10±4.54Metformin 0.25g tid, ramipril 5 mg qd, fenofibrate
200 mg qd
BMI: 26.11±1.57 WC: 87.83±3.73FBG: 6.37±0.58
2hPG: 7.62±0.46
TC: 3.84±0.84
TG: 2.10±0.53
LDL: 2.35±0.24
HDL: 1.05±0.11
SBP: 129.87±3.31 DBP: 79.53±3.89
Ji 201733/3312 weeksChaihu Sanren decoctionBMI: 25.77±2.33 WC: 92.47±7.27FBG: 5.46±0.54TC: 4.03±0.69
TG: 2.04±0.95
LDL: 2.62±0.81
HDL: 1.12±0.16
SBP: 134.85±9.56 DBP: 80.00±10.00Pioglitazone hydrochloride tablets 15 mg qdBMI: 27.85±1.60 WC: 96.85±8.49FBG: 5.40±1.40TC: 4.64±1.04
TG: 2.56±1.10
LDL: 3.22±0.75
HDL: 0.98±0.11
SBP: 141.48±9.32 DBP: 85.00±15.00
Li 201238/3712 weeksTang Zhi PingBMI: 24.43±0.51 WC: 91.86±6.14FBG: 5.73±0.39 2hPG: 7.92±0.76 HbA1c: 5.27±0.31TC: 3.61±1.24
TG: 1.59±0.32
LDL: 2.23±0.72
HDL: 1.06±0.14
SBP: 127.22±8.13 DBP: 80.44±8.58Metformin 0.25 g tidBMI: 24.17±0.49 WC: 91.39±5.83FBG: 5.28±0.27
2hPG: 7.74±0.92
HbA1c: 5.19±0.48
TC: 4.75±1.16
TG: 2.75±0.46
LDL: 3.03±0.33
HD L: 1.05±0.20
SBP: 136.47±8.96 DBP: 79.20±8.83
Wang 201950/5012 weeksYiqi Huazhuo Gushen granules+basic treatmentBMI: 24.34±0.43 WHtR: 0.87±0.05FBG: 6.23±1.31 2hPG: 8.68±2.56 HbA1c: 7.04±1.26TC: 4.24±0.78
TG: 1.62±0.58 LDL: .54±0.71
HDL: 1.19±0.27
SBP: 125.91±7.12 DBP: 78.47±5.35Valsartan
80 mg qd+placebo+basic treatment
BMI: 27.61±2.75 WHtR: 0.94±0.048FBG: 7.06±1.41
2hPG: 10.62±3.24
HbA1c: 7.52±1.36
TC: 4.25±0.68
TG: 1.88±0.44 LDL: 2.55±0.52
HDL: 1.12±0.21
SBP: 130.5 6±7.99 DBP: 79.88±5.43
Yu 2018215/19912 weeksJiangtang Tiaozhi formulaBMI: 27.33±3.34 WC: 94.73±8.29 HC: 102.02±7.23FBG: 8.24±2.35 2hPG: 14.52±4.73 HbA1c: 7.51±1.44TC: 5.06±1.00 TG: 2.79±1.86 LDL: 2.92±0.73Metformin tablets 0.25 g tidBMI: 27.27±3.21 WC: 94.98±9.03 HC: 102.67±7.16FBG: 8.21±2.23 2hPG: 14.83±4.32
HbA1c: 7.57±1.42
TC: 5.21±1.00 TG: 2.82±1.91 LDL: 2.98±0.76
  • BMI, body mass index; C, control group; DBP, diastolic blood pressure; FBG, fasting plasma glucose; HbA1c, glycosylated hemoglobin; HC, hip circumference; HDL, high-density lipoprotein; 2hPG, 2-hour postprandial blood glucose; LDL, low-density lipoprotein; qd, once per day; SBP, systolic blood pressure; T, treatment group; TC, total cholesterol; TCM, traditional Chinese medicine; TG, triglyceride ; tid, three times per day; WC, waist circumference; WHtR, waist-to-height ratio.