Multivariable Cox regression analysis with HRs for incident CTS and UNE in relation to diabetes mellitus
| Variable | Model I* | Model II† | ||
| HR (95% CI)* | P value | HR (95% CI)† | P value | |
| CTS (n=1081) | ||||
| Prevalent DM | 2.52 (1.99 to 3.18) | <0.0001 | 2.10 (1.65 to 2.70) | <0.0001 |
| Age | 0.98 (0.97 to 0.99) | <0.0001 | 0.98 (0.97 to 0.99) | <0.0001 |
| Sex | 1.69 (1.47 to 1.95) | <0.0001 | 1.69 (1.45 to 1.96) | <0.0001 |
| Body mass index | – | – | 1.07 (1.06 to 1.08) | <0.0001 |
| Hypertension | – | – | 0.98 (0.85 to 1.12) | 0.73 |
| Current smoking | – | – | 1.06 (0.92 to 1.23) | 0.38 |
| Alcohol consumption | – | – | 0.99 (0.99 to 1.00) | 0.18 |
| Antihypertensive treatment | – | – | 1.04 (0.88 to 1.24) | 0.62 |
| UNE (n=223) | ||||
| Prevalent DM | 2.51 (1.49 to 4.19) | <0.001 | 2.20 (1.30 to 3.74) | 0.003 |
| Age | 0.95 (0.93 to 0.97) | <0.0001 | 0.96 (0.94 to 0.98) | <0.001 |
| Sex | 0.87 (0.66 to 1.16) | 0.35 | 0.88 (0.65 to 1.19) | 0.39 |
| Body mass index | – | – | 1.06 (1.02 to 1.09) | 0.001 |
| Hypertension | – | – | 0.87 (0.64 to 1.19) | 0.39 |
| Current smoking | – | – | 1.60 (1.21 to 2.15) | 0.001 |
| Alcohol consumption | – | – | 0.99 (0.98 to 1.01) | 0.68 |
| Antihypertensive treatment | – | – | 1.04 (0.70 to 1.54) | 0.83 |
*Adjusted for sex and age at study entry.
†Adjusted for sex, age at study entry, alcohol consumption, body mass index (BMI), hypertension, the use of antihypertensive treatment, and smoking.
CTS, carpal tunnel syndrome; DM, diabetes mellitus; UNE, ulnar nerve entrapment.