Table 1

Characteristics of admissions of patients with diabetes mellitus

VariableAll admissions
(n=1 042 150)
GV (CV 1–4)
(n=416 885)
GV (CV 5–7)
(n=312 624)
GV (CV 8–10)
(n=312 641)
Adjusted
p value
Age (years)*66.5 (10.8)66.1 (10.7)66.6 (10.7)66.8 (10.9)<0.001
A1c7.8 (1.9)7.5 (1.8)7.7 (1.9)8.1 (2.1)<0.001
Male sex, n (%)1 012 466 (97.2)404 389 (97)303 904 (97.2)304 173 (97.3)<0.001
BMI (kg/m2)†29.8 (25.7–34.8)30.4 (26.3–35.4)30.0 (25.9–34.9)28.9 (24.8–33.7)<0.001
 Race, n (%)
 White746 704 (71.7)302 472 (72.6)224 713 (71.9)219 519 (70.2)<0.001
 Black205 090 (19.7)79 399 (19)60 370 (19.3)65 321 (20.9)
 Asian/American Indian/Pacific18 957 (1.8)7563 (1.8)5767 (1.84)5627 (1.8)
 Other/Unknown71 399 (6.9)27 451 (6.6)21 774 (7)22 174 (7.1)
Income (US$), n (%)
 <20 000601 841 (57.8)240 379 (57.7)180 234 (57.7)181 228 (60)<0.001
 20 001–40 000343 421 (33.0)136 717 (32.8)103 299 (33.0)103 405 (33.1)
 40 001–60 00056 350 (5.4)22 866 (5.5)16 912 (5.4)16 572 (5.3)
 >60 00140 538 (3.9)16 923 (4.1)12 179 (3.9)11 436 (3.7)
 LOS (days)†3.9 (2.2–6.9)3.9 (2.2–6.7)3.9 (2.2–6.8)4.00 (2.3–7.00)<0.001
 Hypoglycemia, n (%)‡76 621 (7.4)5203 (1.3)10 902 (3.5)60 516 (19.4)<0.001
Year of admission, n (%)
 Before 2005204 954 (19.7)81 411 (19.5)59 462 (19.0)64 081 (20.5)<0.001
 2006–2010431 271 (41.4)167 179 (40.1)128 592 (41.1)135 500 (43.3)
 2011–2015405 925 (39.0)168 295 (40.4)124 570 (39.9)113 060 (36.2)
Admission source, n (%)
 Nursing home29 777 (2.9)11 833 (2.8)9108 (2.9)8836 (2.8)0.48
 Transfers from OSH28 122 (2.7)11 133 (2.7)8642 (2.8)8347 (2.7)
 Home/Outpatient984 251 (94.4)393 919 (94.5)294 874 (94.3)295 458 (94.5)
Admitting service, n (%)
 Medicine841 242 (80.7)322 961 (77.5)254 065 (81.3)264 216 (84.5)<0.00
 Surgery200 908 (19.3)93 924 (22.53)58 559 (18.7)48 425 (15.5)
DM medications, n (%)
 Insulin635 152 (61.0)235 609 (56.5)193 937 (62)205 606 (65.8)<0.001
 NIM57 026 (5.5)29 019 (7)16 540 (5.3)11 467 (3.7)
 NIM and insulin232 960 (22.4)85 470 (20.5)69 867 (22.4)77 623 (24.8)
 None117 012 (11.2)66 787 (16)32 280 (10.3)17 945 (5.7)
Comorbid conditions, n (%)
 Alcohol abuse52 701 (5.1)21 273 (5.1)15 739 (5)15 689 (5)1
 Blood loss anemia9240 (0.9)3604 (0.9)2821 (0.9)2815 (0.0)1
 Cardiac arrhythmia239 084 (22.9)94 426 (22.7)73 068 (23.4)71 590 (22.9)<0.001
 CHF252 302 (24.2)91 616 (22)77 377 (24.8)83 309 (26.7)<0.001
 COPD226 848 (21.8)86 918 (20.9)67 995 (21.8)71 935 (23)<0.001
 Coagulopathy30 557 (2.9)11 902 (2.9)9436 (3)9219 (3)0.008
 Deficiency anemia46 229 (4.4)17 127 (4.1)13 884 (4.4)15 218 (4.9)<0.001
 Depression128 659 (12.4)52 794 (12.7)38 313 (12.3)37 552 (12)<0.001
 Drug abuse23 302 (2.2)8810 (2.1)6757 (2.2)7735 (2.5)<0.001
 Fluid/Electrolyte181 170 (17.4)67 928 (16.3)54 448 (17.4)58 794 (18.8)<0.001
 HIV/AIDS4366 (0.4)1725 (0.41)1346 (0.43)1295 (0.41)1
 Hypothyroidism70 271 (6.7)27 787 (6.7)21 222 (6.8)21 262 (6.8)1
 Hypertension (complicated)210 652 (20.2)72 536 (17.4)64 401 (20.6)73 715 (23.6)<0.001
 Liver disease72 858 (7.0)28 344 (6.8)22 293 (7.1)22 221 (7.1)<0.001
 Lymphoma11 900 (1.1)4708 (1.1)3633 (1.2)3559 (1.1)1
 Metastatic cancer25 685 (2.5)11 231 (2.7)7667 (2.5)6787 (2.2)<0.001
 Solid tumor non-met86 514 (8.3)37 739 (9.1)25 651 (8.2)23 124 (7.4)<0.001
 Myocardial infarction64 594 (6.2)24 958 (6)19 635 (6.3)20 001 (6.4)<0.001
 Neurological disorder43 784 (4.2)17 713 (4.3)13 187 (4.2)12 884 (4.1)0.93
 Obesity89 885 (8.6)41 097 (9.9)27 182 (8.7)21 606 (6.9)<0.001
 Paralysis15 558 (1.5)6723 (1.6)4787 (1.5)4048 (1.3)<0.001
 Peptic ulcer disease8129 (0.8)3315 (0.8)2450 (0.8)2364 (0.8)1
 PVD102 132 (9.8)38 293 (9.2)30 793 (9.9)33 046 (10.6)<0.001
 Psychosis26 010 (2.5)10 334 (2.5)7761 (2.5)7915 (2.5)1
 Pulm/Circ disease33 094 (3.2)12 561 (3)10 192 (3.3)10 341 (3.3)<0.001
 Renal failure238 635 (22.9)81 843 (19.6)72 712 (23.3)84 080 (26.9)<0.001
 Rheumatoid arthritis13 559 (1.3)4938 (1.2)4027 (1.3)4594 (1.5)<0.001
 Valvular disease48 174 (4.6)18 657 (4.5)14 721 (4.7)14 796 (4.7)<0.001
 Weight loss21 410 (2.0)8065 (1.9)6513 (2.1)6832 (2.2)<0.001
  • *Mean (SD).

  • †Median (IQR).

  • ‡Hypoglycemia within past 24 hours.

  • A1c, hemoglobin A1c; BMI, body mass index; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; CV, coefficient of variation; DM, diabetes mellitus; GV, glucose variability; LOS, length of stay; NIM, non-insulin medications; non-met, non-metastatic; OSH, outside hospital; Pulm/Circ, pulmonary or circulatory disorders; PVD, peripheral vascular disease.