Vitamin B12 and homocysteine in non-metformin and metformin users
| Parameters | Metformin use | P value | |
| No | Yes | ||
| Vitamin B12 | |||
| Deficiency (<200) | 6 (2.1%) | 25 (3.9%) | 0.002 |
| Insufficiency (200–300) | 80 (27.9%) | 117 (18.4%) | |
| Normal (>300) | 200 (70%) | 494 (77.7%) | |
| B12 levels and homocysteine | |||
| B12 deficient and homocysteine | |||
| Normal | 0 (0%) | 6 (24%) | 0.197 |
| Hyper | 6 (100%) | 19 (76%) | |
| B12 insufficient and homocysteine | |||
| Normal | 21 (26.9%) | 45 (39.4%) | 0.05 |
| Hyper | 57 (73.1%) | 69 (60.5%) | |
| Overall homocysteine | |||
| Normal | 21 (25%) | 51 (36.7%) | 0.047 |
| Hyper | 63 (75%) | 88 (63.3%) | |
Data presented as n (%).
χ2 test was applied.
P<0.05 considered to be statistically significant.