Promoter region variants | T2DM (n=80) | Exon/intron variants | T2DM (n=80) | ||
c.-385 A>G (rs3859206) | AA | 0.31 | c.2 T>A | TT | 0.99 |
AG | 0.54 | AT | 0.01 | ||
GG | 0.15 | AA | / | ||
G-allele | 0.42 | A-allele | 0.01 | ||
c.-232 A>T (rs 2256339) | AA | 0.27 | c.187 A>C (rs2253149) | AA | / |
AT | 0.58 | AC | / | ||
TT | 0.15 | CC | 1 | ||
T-allele | 0.44 | C-allele | 0.01 | ||
c.-421 C>T | CC | 0.99 | IVS2-27 A>T | AA | 0.99 |
CT | 0.01 | AT | 0.01 | ||
TT | / | TT | / | ||
T-allele | 0.01 | T-allele | 0.01 | ||
c.-429delATCGGAG | +/+ | 0.99 | IVS2 +26 A>G (rs2253132) | AA | 1 |
+/del | 0.01 | AG | / | ||
del/del | / | GG | / | ||
del | 0.01 | A-allele | 0.01 | ||
IVS2 +31 A>T (rs2253131) | AA | / | |||
AT | 0.19 | ||||
TT | 0.81 | ||||
A-allele | 0.09 | ||||
c.465 G>A | GG | 0.99 | |||
AG | 0.01 | ||||
AA | / | ||||
A-allele | 0.01 | ||||
IVS4-9delTTG (rs72318398) | +/+ | 0.74 | |||
+/del | 0.25 | ||||
del/del | 0.01 | ||||
del | 0.14 | ||||
c.900 C>G (rs1056534) | CC | 0.15 | |||
GC | 0.48 | ||||
GG | 0.37 | ||||
C-allele | 0.39 | ||||
c.906 C>T (rs149413139) | CC | 0.98 | |||
CT | 0.03 | ||||
TT | / | ||||
T-allele | 0.01 |
Values for genotypes and rare alleles are frequencies.
rs ID: http://www.ncbi.nlm.nih.gov/snp/.
β+β symbol indicates the wild-type allele; βdelβ denotes the allele characterized by the deletion.
FN3K, fructosamine-3-kinase; rs, RefSNP; T2DM, type 2 diabetes mellitus.