Summary HIP (percentage) incidence and population insulin sensitivity (KxgI) statistics for baseline and scaling up and scaling back scenarios simulated from 2018 to 2060
HIP incidence (%) | 2020 | 2030 | 2040 | 2050 | 2060 | ||||||||||
% | 95% CI (±) | % change from baseline | % | 95% CI (±) | % change from baseline | % | 95% CI (±) | % change from baseline | % | 95% CI (±) | % change from baseline | % | 95% CI (±) | % change from baseline | |
Baseline | 15.6 | 0.28 | 15.8 | 0.31 | 16.9 | 0.31 | 17.2 | 0.3 | 17.0 | 0.3 | |||||
Scenario A: all normal weight | 15.9 | 0.26 | 1.8 | 15.9 | 0.31 | 0.8 | 17.1 | 0.31 | 1.4 | 17.0 | 0.3 | −0.9 | 13.4* | 0.3 | −21.2 |
Scenario B: more overweight or obese | 15.7 | 0.27 | 0.4 | 15.7 | 0.30 | −0.6 | 17.1 | 0.27 | 1.3 | 17.3 | 0.3 | 0.4 | 17.6 | 0.3 | 3.8 |
Insulin sensitivity (KxgI) | 2020 | 2030 | 2040 | 2050 | 2060 | ||||||||||
Mean | 95% CI (±) | % change from baseline | Mean | 95% CI (±) | % change from baseline | Mean | 95% CI (±) | % change from baseline | Mean | 95% CI (±) | % change from baseline | Mean | 95% CI (±) | % change from baseline | |
Baseline | 50.3 | 0.02 | 48.4 | 0.02 | 46.4 | 0.03 | 45.7 | 0.02 | 45.6 | 0.02 | |||||
Scenario A: all normal weight | 50.9 | 0.02 | 1.2 | 52.5 | 0.02 | 8.5 | 54.2 | 0.03 | 16.9 | 60.0 | 0.03 | 31.2 | 67.1 | 0.04 | 47.3 |
Scenario B: more overweight or obese | 49.7 | 0.02 | −1.2 | 44.6 | 0.02 | −7.8 | 39.3 | 0.02 | −15.4 | 34.7 | 0.02 | −24.1 | 31.5 | 0.02 | −30.9 |
KxgI: an index of insulin sensitivity representing insulin-dependent glucose tissue reuptake.
*Significantly different from baseline at p<0.05.
HIP, hyperglycemia in pregnancy.