Table 3

Association between exposure to recent and lifetime diabetic ketoacidosis (DKA) and having the lowest cognitive function in our sample (1.5 SD below population mean)

Model outcomeNumber with lowest functionAdjusted for age, sex, race, diagnosis age, education
OR (95% CI)
Global cognition55
 0 DKA hospitalizationReference
 1 DKA hospitalization0.56 (0.22 to 1.42)
 ≥2 DKA hospitalizations1.55 (0.58 to 4.12)
Language48
 0 DKA hospitalizationReference
 1 DKA hospitalization0.67 (0.26 to 1.76)
 ≥2 DKA hospitalizations1.85 (0.67 to 5.09)
Executive function/psychomotor speed57
 0 DKA hospitalizationReference
 1 DKA hospitalization0.64 (0.25 to 1.60)
 ≥2 DKA hospitalizations3.26 (1.43 to 7.42)
Episodic memory59
 0 DKA hospitalizationReference
 1 DKA hospitalization0.74 (0.33 to 1.64)
 ≥2 DKA hospitalizations0.89 (0.30 to 2.66)
Attention48
 0 DKA hospitalizationReference
 1 DKA hospitalization0.71 (0.29 to 1.75)
 ≥2 DKA hospitalizations1.52 (0.58 to 3.96)
  • Association between lowest cognitive function (1.5 SD below population mean) and exposure to lifetime DKA resulting in hospitalization. Values in bold indicate cognitive function scores that were statistically different from the referent group (ie the no DKA group).