Clinical laboratory data after matching
| SGLT2i (N=982) | GLP-1RA (N=800) | SMD* | P value† | |
| Clinical-laboratory data | ||||
| Fasting glucose (mg/dL) | 168.5 (48.4) | 161.5 (42.3) | 0.15 | 0.013 |
| HbA1c (%) | 8.0 (1.1) | 7.8 (0.9) | 0.21 | <0.001 |
| Total cholesterol (mg/dL) | 168.6 (37.8) | 168.8 (37.2) | −0.01 | 0.497 |
| HDL cholesterol (mg/dL) | 47.3 (13.9) | 47.9 (12.8) | −0.04 | 0.142 |
| LDL cholesterol (mg/dL) | 93.6 (33.6) | 93.0 (32.4) | 0.02 | 0.326 |
| Triglycerides (mg/dL) | 137.1 (56.6) | 139.4 (57.4) | −0.04 | 0.237 |
| Systolic blood pressure (mm Hg) | 141.9 (20.9) | 141.9 (18.7) | <0.01 | 0.371 |
| Diastolic blood pressure (mm Hg) | 81.2 (10.6) | 81.1 (10.7) | <0.01 | 0.450 |
Clinical-laboratory data were collected from the visit closest to the index date. SMD values reported as ‘<0.01’ are, in fact, <0.01 and >−0.01.
*SMDs (positive if SGLT2i greater).
†Mann-Whitney test.
GLP-1RA, glucagon-like peptide-1 receptor agonists; HbA1c, glycated hemoglobin; HDL, high density lipoprotein; LDL, low density lipoprotein; SGLT2i, sodium glucose cotransporter-2 inhibitors; SMD, standardized mean difference.