n | Events | Percent events | Events per 1000 patient-years (95% CI), unadjusted | P value | Events per 1000 patient-years (95% CI), age and gender adjusted | P value | |
eGFR deciles | |||||||
1 | 1565 | 148 | 9.5 | 11.84 (10.08 to 13.92) | 0.007 | 14.23 (11.68 to 17.33) | <0.0001 |
2 | 1566 | 170 | 10.9 | 13.65 (11.74 to 15.86) | 0.149 | 11.07 (9.18 to 13.35) | 0.119 |
3 | 1566 | 196 | 12.5 | 15.87 (13.80 to 18.26) | Ref | 9.38 (7.85 to 11.21) | Ref |
4 | 1565 | 261 | 16.7 | 21.74 (19.25 to 24.54) | 0.001 | 9.93 (8.41 to 11.73) | 0.544 |
5 | 1566 | 330 | 21.1 | 28.17 (25.29 to 31.38) | <0.0001 | 10.47 (8.93 to 12.27) | 0.224 |
6 | 1565 | 347 | 22.2 | 29.71 (26.74 to 33.00) | <0.0001 | 10.66 (9.08 to 12.51) | 0.154 |
7 | 1566 | 333 | 21.3 | 28.35 (25.46 to 31.56) | <0.0001 | 10.24 (8.70 to 12.04) | 0.336 |
8 | 1566 | 408 | 26.1 | 35.53 (32.25 to 39.15) | <0.0001 | 11.57 (9.92 to 13.49) | 0.016 |
9 | 1566 | 545 | 34.8 | 50.32 (46.26 to 54.72) | <0.0001 | 14.30 (12.35 to 16.55) | <0.0001 |
10 | 1565 | 864 | 55.2 | 92.51 (86.54 to 98.89) | <0.0001 | 23.66 (20.60 to 27.17) | <0.0001 |
Filtration status | |||||||
Hyper | 644 | 169 | 26.2 | 36.32 (31.24 to 42.23) | <0.0001 | 13.66 (11.30 to 16.51) | 0.009 |
Normo | 12 306 | 2160 | 17.6 | 22.93 (21.98 to 23.92) | Ref | 10.81 (9.57 to 12.21) | Ref |
Hypo | 2706 | 1273 | 47.0 | 73.86 (69.91 to 78.03) | <0.0001 | 19.84 (17.42 to 22.59) | <0.0001 |
eGFR, estimated glomerular filtration rate; RIACE, Renal Insufficiency And Cardiovascular Events.