Baseline demographics for intent-to-treat and per-protocol populations by arm
| Intent-to-treat | Placebo (n=26) | WBF-010 (n=27) | WBF-011 (n=23) |
| Age (years) | 53.7±1.5 | 49.3±2.3 | 51.3±1.7 |
| Female (no. (%)) | 15 (57.7) | 18 (66.7) | 13 (56.5) |
| Ethnicity (no. (%)) | |||
| Hispanic | 13 (50.0) | 15 (55.6) | 15 (65.2) |
| Non-hispanic Caucasian | 11 (42.3) | 6 (22.2) | 5 (21.7) |
| Black | 2 (7.7) | 4 (14.8) | 2 (8.7) |
| Other | 0 (0.0) | 2 (7.4) | 1 (4.4) |
| Weight (kg) | 93.4±4.5 | 92.7±4.1 | 87.6±4.5 |
| Body mass index (kg/m2) | 33.4±1.1 | 34.4±1.1 | 31.9±1.0 |
| A1c (%) | 8.9±0.3 | 8.5±0.3 | 8.8±0.3 |
| Fasting glucose (mg/dL) | 208.8±12.8 | 179.6±12.5 | 179.0±10.9 |
| # D.E./+Met/+SFU | 9/10/7 | 1/20/6 | 4/16/3 |
| Per-protocol | Placebo (n=16) | WBF-010 (n=21) | WBF-011 (n=21) |
| Age (years) | 53.5±2 | 51.2±2.1 | 51.8±1.8 |
| Female (no. (%)) | 12 (75.0) | 14 (66.7) | 12 (57.1) |
| Ethnicity (no. (%)) | |||
| Hispanic | 9 (56.2) | 13 (61.9) | 14 (66.7) |
| Non-hispanic Caucasian | 6 (37.5) | 5 (23.8) | 4 (19.0) |
| Black | 1 (6.3) | 2 (9.5) | 2 (9.5) |
| Other | 0 (0.0) | 1 (4.8) | 1 (4.8) |
| Weight (kg) | 90.8±5.3 | 90.2±5.1 | 86.5±4.3 |
| Body mass index (kg/m2) | 33.5±1.6 | 33.7±1.3 | 31.7±1.1 |
| A1c (%) | 8.2±0.3 | 8.2±0.2 | 8.9±0.3 |
| Fasting glucose (mg/dL) | 180.9±12.4 | 167.5±12.6 | 183.8±11.4 |
| # D.E./+Met/+SFU | 5/7/4 | 0/15/6 | 3/15/3 |
Data are mean±SE unless otherwise noted. D.E./+Met/+SFU, Number of subjects treated with diet and exercise alone, +Metformin, +Sulfonylurea.