Table 1

Sociodemographic and clinical characteristics of patients with diabetes with lower-extremity amputation

			Type of amputation
	Total (1053)		Major (317)		Minor (736)		P value
	n	%	n	%	n	%	P value
Gender
Male	756	71.8	217	68.5	539	73.2	0.114
Female	297	28.2	100	31.5	197	26.8	0.114
Age
35–54	141	13.4	29	9.2	112	15.2	0.002
55–64	247	23.5	67	21.1	180	24.5
65–74	351	33.3	104	32.8	247	33.6
75+	314	29.8	117	36.9	197	26.8
Education level
Low	415	39.4	137	43.2	278	37.9	0.266
Medium	418	39.7	118	37.2	300	40.9
High	218	20.7	62	19.6	156	21.3
Comorbidities*
Vasculopathy	398	37.8	130	41.0	268	36.4	0.158
Neuropathy	70	6.6	25	7.9	45	6.1	0.290
Cardiovascular diseases†	621	59.0	210	66.2	411	55.8	0.009
Cardiovascular risk factors‡	412	39.1	143	45.1	269	36.5	0.002
Neoplasm	56	5.3	19	5.9	37	5.0	0.521
Chronic renal diseases	259	24.6	83	26.2	176	23.9	0.433
Drug consumption§
At least two antidepressant drug prescriptions	152	14.4	56	17.7	96	13.0	0.050
Vital status
Alive	534	50.7	118	37.2	416	56.5	0.643
Died	519	49.3	199	62.8	320	43.5	0.643

*In the 24 months preceding the index date.
†Ischemic disease, heart failure, cerebrovascular disease, vascular disease, previous cardiac revascularization, and cerebrovascular revascularization.
‡Lipid metabolism disorders and hypertension.
§In the 6 months preceding the index date.