Cancer mortality and adjusted HRs (95% CI) for cancer death by 1,5-AG level quartile
| Events/n | Event rate (per 1000 person-years) | Model 1 HR (95% CI) | Model 2 HR (95% CI) | Model 3 HR (95% CI) | |
| Men | |||||
| First quartile | 22/718 | 3.11 | 1 (reference) | 1 (reference) | 1 (reference) |
| Second quartile | 36/709 | 5.42 | 1.95 (1.15 to 3.37) | 1.95 (1.15 to 3.37) | 1.96 (1.16 to 3.38) |
| Third quartile | 30/713 | 4.36 | 1.55 (0.89 to 2.72) | 1.54 (0.89 to 2.71) | 1.54 (0.89 to 2.70) |
| Fourth quartile | 52/702 | 8.00 | 2.62 (1.60 to 4.41) | 2.62 (1.61 to 4.41) | 2.55 (1.56 to 4.31) |
| Women | |||||
| First quartile | 26/996 | 2.53 | 1 (reference) | 1 (reference) | 1 (reference) |
| Second quartile | 23/996 | 2.35 | 1.08 (0.58 to 1.81) | 1.04 (0.59 to 1.82) | 1.04 (0.59 to 1.82) |
| Third quartile | 26/983 | 2.65 | 1.11 (0.64 to 1.92) | 1.12 (0.65 to 1.94) | 1.12 (0.64 to 1.93) |
| Fourth quartile | 34/996 | 3.67 | 1.47 (0.88 to 2.47) | 1.47 (0.88 to 2.48) | 1.45 (0.87 to 2.44) |
Model 1: HR adjusted for age, body mass index, smoking status, alcohol intake, and radiation effects using multiple Cox proportional hazard model.
Model 2: HR adjusted for factors used in model 1 as well as HOMA-R.
Model 3: HR adjusted for factors used in model 2 as well as HbA1c.
1,5-AG, 1,5-anhydroglucitol; HbA1c, glycated hemoglobin; HOMA-R, homeostasis model assessment of insulin resistance.