Criteria | Study | |||||||
14 | 15 | 16 | 17 | 18 | 19 | 20 | ||
Method | ||||||||
Ethical statement | Reported the ethics committee approval | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Study design | Reported control vs Ischemia group | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Animal characteristics | Animal age/weight | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Sex | 1 | 0 | 1 | 1 | 0 | 1 | 1 | |
Strain | 1 | 1 | 1 | 1 | 0 | 1 | 1 | |
Experimental procedures | Detailed the ischemia protocol | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Detailed the wound development protocol | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |
Animal randomization to different groups | Indicated methods employed to minimize selection bias between groups | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Statistics | Reported the statistical methods used for each analysis | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Experimental measurements | Reported the process employed for measurement of wound area | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Reported that the wound measurements were performed in duplicates or blinded to confirm reliability | 0 | 1 | 1 | 0 | 0 | 0 | 0 | |
Results | ||||||||
Baseline data | Reported baseline data for all animal groups | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Numbers analyzed | Reported the absolute number of animals used in each group | 1 | 0 | 1 | 1 | 1 | 1 | 1 |
Data estimation | Reported the results of analysis with a measure of precision (SD or SEM) | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Adverse events | Reported if there was no/any adverse events or infection arising from the wounds | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Score of 15=100% | 12 | 10 | 14 | 12 | 9 | 12 | 12 | |
Total score (%) | 80 | 66.6 | 93.3 | 80 | 60 | 80 | 80 |
1=Yes; 0=No.
ARRIVE, Animal research: Reporting of In Vivo Experiments.