Risk of type 2 diabetes incidence during a 15-year follow-up between categories of selected variables
n of cases (n=417) | N at risk (n=4270) | % | HR* | 95% CI | |
Sociodemographic factors | |||||
Sex | |||||
Women | 176 | 2308 | 54.1 | 1 | |
Men | 241 | 1962 | 45.9 | 1.77 | 1.46 to 2.16 |
Age (years) | |||||
30–39 | 42 | 1215 | 28.5 | 1 | |
40–49 | 109 | 1287 | 30.1 | 2.58 | 1.81 to 3.68 |
50–59 | 175 | 1083 | 25.4 | 5.23 | 3.74 to 7.33 |
60–69 | 91 | 685 | 16.0 | 4.62 | 3.21 to 6.67 |
Education | |||||
Low | 179 | 1285 | 30.1 | 1 | |
Intermediate | 151 | 1523 | 35.7 | 0.91 | 0.72 to 1.14 |
High | 87 | 1462 | 34.2 | 0.59 | 0.45 to 0.77 |
Lifestyle factors | |||||
BMI (kg/m2) | |||||
<25 | 44 | 1704 | 39.9 | 1 | |
25–29.9 | 172 | 1704 | 39.9 | 3.33 | 2.38 to 4.65 |
≥30 | 201 | 862 | 20.2 | 8.59 | 6.18 to 11.9 |
Physical activity | |||||
Low | 123 | 1018 | 23.8 | 1 | |
Moderate | 232 | 2403 | 56.3 | 0.71 | 0.57 to 0.89 |
Regular vigorous training | 62 | 849 | 19.9 | 0.56 | 0.41 to 0.76 |
Alcohol consumption | |||||
No | 111 | 1048 | 24.5 | 1 | |
Moderate | 211 | 2531 | 59.3 | 0.82 | 0.64 to 1.03 |
Heavy | 95 | 691 | 16.2 | 1.35 | 1.01 to 1.79 |
Smoking | |||||
Never | 172 | 2139 | 50.1 | 1 | |
Former smoker | 110 | 872 | 20.4 | 1.37 | 1.07 to 1.76 |
Current smoker | 135 | 1259 | 29.5 | 1.57 | 1.24 to 1.98 |
Energy intake quintiles† (kcal/day) | |||||
First (lowest) | 100 | 853 | 20.0 | 1 | |
Second | 74 | 854 | 20.0 | 0.75 | 0.55 to 1.01 |
Third | 75 | 854 | 20.0 | 0.75 | 0.56 to 1.01 |
Fourth | 72 | 854 | 20.0 | 0.77 | 0.57 to 1.04 |
Fifth | 96 | 855 | 20.0 | 1.05 | 0.79 to 1.39 |
AHEI quintiles‡ | |||||
First (lowest) | 65 | 780 | 18.3 | 1 | |
Second | 88 | 861 | 20.2 | 1.16 | 0.84 to 1.60 |
Third | 100 | 995 | 23.3 | 1.09 | 0.80 to 1.49 |
Fourth | 83 | 800 | 18.7 | 1.16 | 0.84 to 1.60 |
Fifth | 81 | 834 | 19.5 | 0.95 | 0.69 to 1.33 |
Sleep duration (hours) | |||||
≤6 | 74 | 587 | 13.7 | 1 | |
7–8 | 297 | 3239 | 75.9 | 0.77 | 0.59 to 0.99 |
≥9 | 46 | 444 | 10.4 | 0.93 | 0.64 to 1.34 |
Metabolic factors | |||||
Waist circumference (cm) | |||||
<80 cm for women or <94 cm for men | 43 | 1531 | 35.9 | 1 | |
≥80 cm for women or ≥94 cm for men | 374 | 2739 | 64.1 | 4.57 | 3.32 to 6.29 |
Blood pressure | |||||
Normal | 94 | 1901 | 44.5 | 1 | |
Elevated | 323 | 2369 | 55.5 | 2.07 | 1.62 to 2.65 |
Serum triglycerides (mmol/L) | |||||
<1.7 | 189 | 2993 | 70.1 | 1 | |
≥1.7 | 228 | 1277 | 29.9 | 2.54 | 2.08 to 3.10 |
Serum HDL cholesterol (mmol/L) | |||||
≥1.29 for women or ≥1.03 for men | 186 | 2857 | 66.9 | 1 | |
<1.29 for women or <1.03 for men | 231 | 1413 | 33.1 | 2.75 | 2.27 to 3.34 |
Fasting serum glucose (mmol/L) | |||||
<5.6 | 151 | 3041 | 71.2 | 1 | |
≥5.6 | 266 | 1229 | 28.8 | 3.99 | 3.24 to 4.92 |
MetS (IDF definition) | |||||
No | 100 | 2708 | 63.4 | 1 | |
Yes | 317 | 1562 | 36.6 | 5.07 | 4.02 to 6.39 |
Indicators of poor health | |||||
Severe MetS§ | |||||
No | 336 | 4073 | 95.4 | 1 | |
Yes | 81 | 197 | 4.61 | 4.75 | 3.70 to 6.10 |
Mental health¶ | |||||
Good | 314 | 3328 | 78.1 | 1 | |
Poor | 103 | 931 | 21.9 | 1.26 | 1.01 to 1.58 |
Self-perceived health | |||||
Good, quite good or mediocre | 366 | 3980 | 93.3 | 1 | |
Quite poor or poor | 51 | 285 | 6.68 | 1.74 | 1.30 to 2.34 |
Osteoarthritis | |||||
No | 373 | 4043 | 95.4 | 1 | |
Yes | 42 | 194 | 4.58 | 1.68 | 1.21 to 2.34 |
*Adjusted for age and sex.
†Energy intake quintile ranges (kcal): first 732–1755 for male, 593–1613 for female; second 1756–2113 for male, 1614–1946 for female ; third 2114–2478 for male, 1947–2285 for female; fourth 2479–3022 for male, 2286–2677 for female; fifth 3023–6413 for male, 2678–6495 for female.
‡AHEI quintile ranges (points): first 7–16 for male, 7–16 for female; second 17–19 for male, 17–19 for female; third 20–22 for male, 20–22 for female; fourth 23–25 for male, 23–25 for female; fifth 26–34 for male, 26–35 for female.
§Fulfillment of each MetS precondition (according to IDF definition).
¶General Health Questionnaire score >2.
AHEI, Alternate Healthy Eating Index; BMI, body mass index; HDL, high-density lipoprotein; IDF, International Diabetes Federation; MetS, metabolic syndrome; n, number of subjects in respective category.