Risk of type 2 diabetes incidence during a 15-year follow-up between those with and without IWL during the year prior to baseline in categories of different indicators of health in subjects with BMI ≥25 kg/m2 (n=2484)
| Variable | Number of individuals | HR* | 95% CI | P for interaction | |||
| No IWL (ref.) | IWL | ||||||
| Cases | At risk | Cases | At risk | ||||
| Severe MetS†‡ | 0.37 | ||||||
| No | 216 | 1925 | 65 | 373 | 1.87 | 1.41 to 2.48 | |
| Yes | 63 | 160 | 16 | 26 | 2.79 | 1.59 to 4.90 | |
| Mental health§ | 0.74 | ||||||
| Good | 207 | 1638 | 59 | 305 | 1.57 | 1.14 to 2.16 | |
| Poor | 72 | 447 | 22 | 94 | 1.76 | 1.08 to 2.86 | |
| Self-perceived health | 0.25 | ||||||
| Good, quite good or mediocre | 243 | 1909 | 68 | 370 | 1.48 | 1.11 to 1.99 | |
| Quite poor or poor | 36 | 176 | 13 | 29 | 3.05 | 1.60 to 5.80 | |
| Osteoarthritis | 0.78 | ||||||
| No | 248 | 1955 | 73 | 372 | 1.66 | 1.25 to 2.21 | |
| Yes | 31 | 130 | 8 | 27 | 1.30 | 0.59 to 2.85 | |
*Adjusted for sex, age, education, physical activity, alcohol consumption, smoking, energy intake, AHEI, sleep duration, elevated blood pressure, serum HDL cholesterol, serum triglycerides and fasting serum glucose.
†Fulfillment of each MetS precondition (according to IDF definition).
‡Not adjusted for elevated blood pressure, serum HDL cholesterol, serum triglycerides and fasting serum glucose.
§General Health Questionnaire score >2.
AHEI, Alternate healthy eating index; BMI, body mass index; HDL, high-density lipoprotein; IDF, International Diabetes Federation; IWL, intentional weight loss; MetS, metabolic syndrome; n, number of subjects in respective category.