Table 1

Association between annual change in eGFR and variables

VariableUnivariateMultivariate
Coefficient (SE)P valueCoefficient (SE)P value
Age−0.02 (0.02)0.27
SBP0.00 (0.01)0.96
HbA1c0.13 (0.17)0.42
eGFR0.03 (0.01)<0.00010.03 (0.01)<0.0001
Alb/Cr−0.31 (0.20)0.13
SMTNL20.04 (0.02)0.020.04 (0.02)0.02
G6PC0.02 (0.01)0.08
L-FABP/Cr−0.64 (0.37)0.08
NAG/Cr0.54 (0.68)0.42
  • Values mentioned here are regression coefficients (SE).

  • Alb/Cr, urinary log-transformed albumin-to-creatinine ratio; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin A1c; L-FABP/Cr, urinary log-transformed liver-type fatty acid-binding protein-to-creatinine ratio; NAG/Cr, urinary log-transformed N-acetyl-β-D-glucosaminidase-to-creatinine ratio; SBP, systolic blood pressure; SMTNL2, DNA methylation levels of SMTNL2 in urine sediment.