NGT (0) | mGA (1) | PRE (2) | DIA (3) | P overall | 0 vs 1 | 0 vs 2 | 0 vs 3 | 1 vs 2 | 1 vs 3 | 2 vs 3 | |
n | 126 (24%) | 377 (71%) | 24 (5%) | 4 (0.8%) | |||||||
Age (years) | 56.8±9.4 | 60.4±8.4 | 62.9±8.5 | 68.4±5.2 | <0.0001 | 0.0015 | 0.0196 | 0.0800 | 0.3836 | 0.2014 | 0.5966 |
Sex | 0.0300* | ||||||||||
Female | 73 (57.94%) | 223 (59.2%) | 7 (29.2%) | 2 (20.0%) | |||||||
Male | 53 (42.1%) | 154 (40.8%) | 17 (70.8%) | 2 (50.0%) | |||||||
FINDRISC | 12.2±3.1 | 13.8±3.7 | 16.2±4.0 | 19.5±4.1 | <0.0001 | <0.0001 | <0.0001 | 0.0163 | 0.0176 | 0.0624 | 0.6736 |
DBP (mm Hg) | 75.5±11.5 | 75.7±11.6 | 85.5±10.7 | 80.0±8.2 | 0.0012 | 1.0000 | 0.0014 | 0.8665 | 0.0006 | 0.8495 | 0.6864 |
SBP (mm Hg) | 126.5±14.9 | 127.7±14.7 | 138.6±13.0 | 145.0±12.9 | 0.0002 | 0.7799 | 0.0004 | 0.0924 | 0.0015 | 0.1258 | 0.7963 |
BMI (Kg/m2) | 26.1±4.3 | 27.2±4.6 | 29.3±4.2 | 29.8±2.4 | 0.0010 | 0.0594 | 0.0046 | 0.1973 | 0.0867 | 0.3606 | 0.9243 |
CV risk | 5.0±5.2 | 6.5±6.7 | 10.4±7.2 | 15.5±5.5 | <0.0001 | 0.0496 | 0.0005 | 0.0218 | 0.0090 | 0.0432 | 0.3924 |
SAF (fluorescence unit) | 2.0±0.4 | 2.2±0.4 | 2.3±0.4 | 2.3±0.3 | <0.0001 | <0.0001 | 0.0040 | 0.3035 | 0.3591 | 0.8450 | 0.9997 |
1hPG (mg/dL) | 123.5±36.1 | 155.9±43.9 | 202.6±28.0 | 275.0±17.9 | <0.0001 | <0.0001 | <0.0001 | 0.0038 | <0.0001 | 0.0039 | 0.0088 |
TC (mg/dL) | 200.3±34.9 | 209.4±36 | 196.5±31.6 | 185.8±38.1 | 0.0179 | 0.0415 | 0.9821 | 0.8307 | 0.3240 | 0.6105 | 0.9443 |
TAG (mg/mL) | 107.8±70.3 | 118.4±63 | 139.4±78.7 | 116.5±25.7 | 0.0052 | 0.0135 | 0.0379 | 0.5492 | 0.4956 | 0.9559 | 1.0000 |
HDL (mg/mL) | 58.8±17.6 | 56.6±13.8 | 50.2±16.9 | 52.0±26.4 | 0.0131 | 0.6506 | 0.0162 | 0.5489 | 0.0341 | 0.6336 | 0.9792 |
LDL (mg/mL) | 120.2±28.8 | 129.1±30.7 | 118.5±28.4 | 110.5±34.1 | 0.0160 | 0.0301 | 0.9955 | 0.8407 | 0.4561 | 0.5289 | 0.9349 |
INS (mIU/L) | 10.7±6.7 | 17.5±24.4 | 20.4±9.8 | 17.9±5.7 | <0.0001 | 0.0005 | <0.0001 | 0.0706 | 0.0009 | 0.3228 | 0.9530 |
HOMA-IR | 2.2±1.6 | 4.0±5.6 | 5.4±2.7 | 5.8±1.7 | <0.0001 | <0.0001 | <0.0001 | 0.0128 | <0.0001 | 0.0669 | 0.9530 |
MA (mg/mL) | 13.2±50.7 | 15.8±50.1 | 17.4±16.5 | 9.5±6.2 | 0.0888 | 0.5609 | 0.0724 | 0.8641 | 0.2096 | 0.9434 | 0.9640 |
Kruskal-Wallis test.
*χ2 test.
BMI, body mass index; CV risk, cardiovascular risk; DBP, diastolic blood pressure; DIA, diabetes; FINDRISC, Finnish Diabetes Risk Score; HDL, high-density lipoprotein; HOMA-IR, homeostatic model assessment for insulin resistance; 1hPG, 1-hour plasma glucose; INS, insulinemia; LDL, low-density lipoprotein; MA, microalbuminuria; mGA, miscellaneous glucose abnormalities; NGT, normoglycemia; PRE, pre-diabetes; SAF, skin autofluorescence; SBP, systolic blood pressure; TAG, triacylglycerol; TC, total cholesterol.