Table 5

Only weight reduction model

Biological factors related to hyperglycemiaThresholdRelevance
Fasting glucose<118–133 mg/dL0.07
A1c reduction speed>−0.10 point HbA1c/year0.81
Distance from target 7%<0.7–0.9 point HbA1c0.12
Biological factors related to insulin resistanceThresholdRelevance
BP systolic<115–125 mm Hg0.03
Total cholesterol<189 mg/dL0.04
Triglycerides<125 mg/dL0.02
Hystory and careThreshold or conditionRelevance
Years of observation>100.16
Interval between visits (yeras)<0.4–0.60.28
Diabetes therapyConditionRelevance
SGLT2i, GLP1-RA, DPP-4i, INS+SGLT2 i, INS+GLP1 RA, INS+DPP-4iPresent0.09
  • The model identifies the following factors as relevant for achieving the target: AUC 0.55, accuracy 0.62, sensitivity 0.65, specificity 0.48, precision 0.82, NPV 0.29.

  • AUC, area under the curve; BMI, body mass index; BP, blood pressure; DPP-4i, dipeptidyl peptidase 4 inhibitor; GLP-1RA, glucagon-like peptide-1 receptor agonists; HDL, high density lipoprotein; INS, insulin; NPV, negative predictive value; SGLT2i, sodium-glucose cotransporter-2 inhibitors.