Biological factors related to hyperglycemia | Threshold | Relevance |
Fasting glucose | <118–133 mg/dL | 0.66 |
A1c reduction speed | >−0.10 point HbA1c/year | 0.59 |
Distance from target 7% | <0.7–0.9 point HbA1c | 0.59 |
Biological factors related to insulin resistance | Threshold | Relevance |
BP systolic | <115–125 mm Hg | 0.04 |
Total cholesterol | <189 mg/dL | 0.01 |
Triglycerides | <125–130 mg/dL | 0.08 |
HDL | >47 | 0.04 |
Comorbidity | Condition | Relevance |
Nephropathy | Absent | 0.03 |
Albuminuria | Absent | 0.03 |
Retinopathy | Absent | 0.03 |
Liver disease | Absent | 0.03 |
History and care | Threshold or condition | Relevance |
Years of observation | <5 | 0.16 |
Months of follow-up | <0,9 | 0.28 |
Q Score | >27–30 | 0.10 |
Sex | Male | 0.03 |
Diabetes therapy | Condition | Relevance |
Insulin alone | Present | 0.73 |
Any oral agents | Present | 0.73 |
The model identifies the following factors as relevant for achieving the target: AUC 0.74, accuracy 0.74, sensitivity 0.74, specificity 0.74, precision 0.72, NPV 0.76.
AUC, area under the curve; BP, blood pressure; HDL, high density lipoprotein; NPV, negative predictive value.