Patient with obesity | P value | Patients with obesity with T2DM | P value | |||
Presurgery | Postsurgery | Presurgery | Postsurgery | |||
Weight, kg | 118.1±26.89 | 91±22.29 | <0.001 | 114.36±32.44 | 87.86±27.57 | <0.001 |
BMI, kg/m2 | 40.94±5.97 | 31.29±4.75 | <0.001 | 40.34±9.02 | 30.78±7.12 | <0.001 |
Systolic BP, mm Hg | 127.22±10.74 | 128.11±16.52 | 0.786 | 131.18±8.33 | 128.64±14.6 | 0.490 |
Diastolic BP, mm Hg | 75.56±8.56 | 76.94±10.46 | 0.649 | 78.73±3.04 | 79.82±8.08 | 0.682 |
WBC, µL | 8055.56±2130.24 | 7222.22±1967.55 | 0.102 | 9385.71±2342.21 | 7457.14±1810.53 | <0.001 |
BUN, mg/dL | 11.37±2.47 | 10.19±2.89 | 0.036 | 32.29±62.23 | 23.01±36.17 | 0.211 |
Serum Cr, mg/dL | 0.73±0.15 | 0.72±0.12 | 0.552 | 3.76±11.01 | 3.3±9.42 | 0.305 |
eGFR CKD-EPI by Cr, mL/min/1.73 m2 | 116.27±10.65 | 116.87±8.38 | 0.726 | 107.3±37.24 | 102.85±27.4 | 0.441 |
Cystatin C, mg/L | 0.86±0.09 | 0.83±0.1 | 0.009 | 3±7.21 | 2.52±5.62 | 0.275 |
eGFR CKD-EPI by cysC, mL/min/1.73 m2 | 105.86±10.47 | 109.95±11.42 | 0.020 | 93.65±37.46 | 96.42±33.03 | 0.356 |
AST, U/L | 40.67±22.87 | 20.56±5.79 | <0.001 | 35.42±25.06 | 19.38±8.06 | 0.027 |
ALT, U/L | 69.22±42.94 | 23.67±16.25 | <0.001 | 51.97±45.73 | 19.04±9.6 | 0.015 |
Total cholesterol, mg/dL | 216.28±41.22 | 179.83±26.31 | <0.001 | 183.74±49.05 | 158.43±43.66 | 0.032 |
Triglyceride, mg/dL | 193.28±115.84 | 111.67±49.84 | 0.001 | 205.57±70.61 | 123.93±40.96 | <0.001 |
LDL cholesterol, mg/dL | 148.67±41.13 | 118.33±25.83 | <0.001 | 118.33±49.76 | 95.9±41.12 | 0.045 |
HDL cholesterol, mg/dL | 46.83±9.61 | 55.67±11.24 | <0.001 | 45.91±15.98 | 51.98±17.29 | 0.009 |
Glucose, mg/dL | 107.61±16.26 | 98.22±10.14 | 0.035 | 148.58±51.09 | 104.46±52.67 | 0.011 |
HbA1c | 5.68±0.27 | 5.11±0.3 | <0.001 | 7.79±1.67 | 5.79±0.79 | <0.001 |
Urinary protein, mg/day | 109.51±74.02 | 80.35±30.25 | 0.038 | 223.96±306.31 | 133.28±157.08 | 0.048 |
Urinary albumin, mg/day | 19.47±31.12 | 10.74±9.99 | 0.166 | 101.38±211 | 48.87±112.19 | 0.086 |
Urinary Cr, mg/dL | 1.68±0.71 | 1.46±0.52 | 0.049 | 2.08±1.53 | 1.62±1.07 | 0.019 |
C-peptide, ng/mL | 4.78±1.93 | 3.07±1.48 | 0.006 | 3.72±1.63 | 2.52±0.92 | 0.015 |
Data are presented as means±SD or median (IQR). Differences between patients with obesity and patients with obesity with T2DM were assessed using Student’s t-test and Mann-Whitney U test. The sex variables were evaluated using χ2 test.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; BP, blood pressure; BSA, body surface area; BUN, blood urea nitrogen; CKD-EPI, CKD Epidemiology Collaboration; Cr, creatinine; eGFR, estimated glomerular filtration rate; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; T2DM, type 2 diabtes mellitus; WBC, white blood cell.