Regression of MetS in group B according to characteristics at baseline
| At risk (n) | Regression to no MetS (n) | P value | OR (95% CI) | Person-year | Incidence per 1000 person-years (95% CI) | |
| All samples | 735 | 148 (20.1) | 5556 | 36 (31 to 41) | ||
| Gender | ||||||
| Men | 383 | 59 (15.4) | 1 | 2911 | 20 (15 to 26) | |
| Women | 352 | 89 (25.3) | 0.001 | 1.86 (1.29 to 2.68) | 2645 | 34 (27 to 41) |
| Age (years) | ||||||
| 18–45 | 146 | 42 (28.8) | 1.77 (0.76 to 4.12) | 1092 | 39 (28 to 52) | |
| 46–60 | 265 | 51 (19.2) | 1.04 (0.46 to 2.38) | 1998 | 26 (19 to 34) | |
| 61–75 | 281 | 47 (16.7) | 0.88 (0.38 to 2.01) | 2135 | 22 (16 to 29) | |
| >76 | 43 | 8 (18.6) | 0.029 | 1 | 330 | 24 (11 to 48) |
| Marital status | ||||||
| Single | 61 | 17 (27.9) | 1 | 465 | 37 (21 to 59) | |
| Married/cohabiting | 605 | 119 (19.7) | 0.63 (0.35 to 1.15) | 4579 | 26 (22 to 31) | |
| Widower | 46 | 7 (15.2) | 0.47 (0.17 to 1.24) | 342 | 21 (8 to 42) | |
| Divorced | 23 | 5 (21.7) | 0.380 | 0.72 (0.23 to 2.24) | 169 | 30 (10 to 69) |
| Educational level | ||||||
| No studies | 134 | 23 (17.2) | 1 | 1013 | 23 (14 to 34) | |
| Elementary | 387 | 76 (19.6) | 1.18 (0.71 to 1.97) | 2931 | 26 (20 to 32) | |
| Secondary education | 143 | 33 (23.1) | 1.45 (0.80 to 2.62) | 1072 | 31 (21 to 43) | |
| University degree | 71 | 16 (22.5) | 0.611 | 1.40 (0.69 to 2.87) | 540 | 30 (17 to 48) |
| Region of the country | ||||||
| North | 68 | 19 (27.9) | 1 | 531 | 36 (22 to 56) | |
| South | 285 | 57 (20.0) | 0.65 (0.35 to 1.18) | 2100 | 27 (21 to 35) | |
| Center | 205 | 32 (15.6) | 0.48 (0.25 to 0.91) | 1589 | 20 (14 to 28) | |
| Northeast | 83 | 19 (22.9) | 0.77 (0.37 to 1.60) | 653 | 29 (18 to 45) | |
| East coast | 94 | 21 (22.3) | 0.209 | 0.74 (0.36 to 1.52) | 684 | 31 (19 to 47) |
| Number of components of MetS | ||||||
| 3 | 408 | 111 (27.2) | 5.98 (2.36 to 15.15) | 3086 | 36 (30 to 43) | |
| 4 | 242 | 32 (13.2) | 2.44 (0.92 to 6.48) | 1835 | 17 (12 to 25) | |
| 5 | 85 | 5 (5.9) | 0.000 | 1 | 635 | 8 (3 to 18) |
| Glucose regulation | ||||||
| Normal | 145 | 37 (25.5) | 1.48 (0.97 to 2.27) | 1095 | 34 (24 to 47) | |
| >99 | 580 | 111 (18.8) | 0.048 | 1 | 4461 | 25 (21 to 30) |
| HDL-chol, low | ||||||
| No | 386 | 74 (19.2) | 0.88 (0.62 to 1.26) | 2924 | 25 (20 to 32) | |
| Yes | 349 | 74 (21.2) | 0.276 | 1 | 2632 | 28 (22 to 35) |
| Central obesity | ||||||
| No | 58 | 17 (29.3) | 1.73 (0.95 to 3.14) | 436 | 39 (23 to 62) | |
| Yes | 677 | 131 (19.4) | 0.054 | 1 | 5120 | 26 (21 to 30) |
| Hypertension | ||||||
| No | 84 | 32 (38.1) | 2.84 (1.75 to 4.61) | 627 | 51 (35 to 72) | |
| Yes | 651 | 116 (17.8) | 0.000 | 1 | 4929 | 24 (20 to 28) |
| Hyper-TG | ||||||
| No | 385 | 94 (24.4) | 1.77 (1.22 to 2.57) | 2926 | 32 (26 to 39) | |
| Yes | 350 | 54 (15.4) | 0.002 | 1 | 2630 | 21 (15 to 27) |
| BMI (kg/m2) | ||||||
| 18–<25 | 33 | 19 (57.6) | 0.000 | 1 | 251 | 76 (46 to 118) |
| 25–<30 | 309 | 74 (23.9) | 0.23 (0.11 to 0.49) | 2342 | 32 (25 to 40) | |
| ≥30 | 389 | 55 (14.1) | 0.12 (0.06 to 0.26) | 2934 | 19 (14 to 24) | |
| IPAQ | ||||||
| High | 118 | 28 (23.7) | 0.534 | 1 | 893 | 31 (21 to 45) |
| Moderate | 248 | 49 (19.8) | 0.79 (0.47 to 1.34) | 1887 | 26 (20 to 34) | |
| Low | 368 | 70 (19.0) | 0.76 (0.46 to 1.24) | 2768 | 25 (20 to 32) | |
| MET-min/week | ||||||
| >2000 | 222 | 51 (23.0) | 0.113 | 1.29 (0.88 to 1.89) | 1680 | 30 (23 to 40) |
| <2000 | 512 | 96 (18.8) | 1 | 3868 | 24 (20 to 30) | |
| MEDAS | ||||||
| <9 | 235 | 59 (25.1) | 0.015 | 1 | 1777 | 33 (25 to 43) |
| ≥9 | 500 | 89 (17.8) | 0.65 (0.45 to 0.94) | 3779 | 24 (19 to 29) | |
| >11 | 20 | 5 (25) | 0.376 | 1.33 (0.48 to 3.73) | 149 | 34 (11 to 78) |
| ≤11 | 715 | 143 (20) | 1 | 5406 | 26 (22 to 31) | |
| Family history of T2DM | ||||||
| No | 302 | 64 (21.2) | 0.251 | 1 | 2303 | 28 (21 to 36) |
| Yes | 408 | 77 (18.9) | 0.87 (0.60 to 1.25) | 3061 | 25 (20 to 31) | |
Data are n (%).
BMI, body mass index; HDL-chol, high-density lipoprotein cholesterol; IPAQ, International Physical Activity Questionnaire; MEDAS, MedDiet adherence screener; MET, metabolic equivalent of task; MetS, metabolic syndrome; T2DM, type 2 diabetes mellitus; TG, triglyceride.