Table 2

Continuous glucose monitoring parameters before and after lockdown in Italy due to COVID-19 pandemic in children (≤12 years), teenagers (13–17 years), and adults (≥18 years)

Children (≤12 years)
(n=30)
Teenagers (13–17 years)
(n=24)
Adults (≥18 years)
(n=76)
PrelockdownDuring lockdownP valuePrelockdownDuring lockdownP valuePrelockdownDuring lockdownP value
Sensor use (%)96.5 (87.5–98.8)96.2 (89.3–98.2)0.93797 (93.4–98.5)96.9 (91.4–98.6)0.19895.1 (91–97.5)95 (88.4–97.8)0.279
Mean glucose (mg/dL)181 (161–206)178 (162–199)0.237168 (141–180)164 (139–178)0.354164 (145–191)160 (141–175)0.001
Median glucose (mg/dL)171 (153–196)170 (154–190)0.322157 (135–172)154 (133–169)0.378159 (137–189)154 (133–168)<0.001
GMI (%)7.7 (7.2–8.3)7.6 (7.2–8.1)0.2377.4 (6.7–7.6)7.3 (6.6–7.6)0.3547.3 (6.8–7.9)7.2 (6.7–7.5)0.001
GMI (mmol/mol)60 (55–67)59 (55–65)0.23757 (50–60)56 (49–59)0.35456 (51–63)55 (50–59)0.001
SD (SDglu)67.4 (58.6–74.8)64.3 (55.5–75.2)0.02959.1 (48.6–66.9)55.9 (47.6–66.8)0.61163 (54–70.9)59.6 (52.2–69.3)0.016
Percent CV (%)37.4 (33.4–40.4)36.8 (33.1–39.6)0.06936.3 (32.4–41.6)35.2 (32.2–39.5)0.86236.6 (33.1–41.8)36.3 (33.4–42.3)0.842
TIR (%)53.3 (39.8–62)53.8 (43.4–62.7)0.05561 (50.8–72.4)60.6 (54.9–73.6)0.21357.7 (43.5–67.3)61.3 (53.7–68.3)<0.001
TBR1 (%)1.2 (0.7–2.7)1.3 (0.5–1.8)0.0721.6 (0.6–4.9)1.1 (0.4–4.2)0.8232.5 (1.1–5.4)3 (1.2–5.7)0.019
TBR2 (%)0.4 (0.0–0.8)0.3 (0–0.4)0.0290.2 (0–0.7)0.1 (0.1–0.7)0.4200.4 (0.1–1.7)0.5 (0.1–1.6)0.419
TAR1 (%)28.1 (25.1–31.0)27.3 (24.3–32.9)0.88624.4 (17.5–34.4)25.5 (16.4–32.4)0.41426.5 (19.3–31.7)25.1 (19–29.4)0.001
TAR2 (%)14.5 (9–26.3)14.6 (7.2–22.5)0.0749.6 (4.3–15.2)7.4 (2.9–16.7)0.40811.1 (4.5–19)7.8 (4.4–13)0.007
Low Blood Glucose Index0.5 (0.3–0.9)0.5 (0.2–0.6)0.0330.7 (0.2–1.3)0.5 (0.3–1.4)0.7130.8 (0.4–1.7)0.8 (0.4–1.7)0.047
High Blood Glucose Index10.3 (7.5–15)9.6 (7.4–13.7)0.1018.3 (5–10.1)7.7 (4.2–10.3)0.3998.3 (5.4–12.2)7.2 (4.9–9.5)0.002
  • Data are expressed as median with IQR in parentheses. P values refer to paired samples t-tests performed for each parameter in the three groups of patients divided by age range. TIR: 70–180 mg/dL, TBR1: 54–69 mg/dL, TBR2 <54 mg/dL, TAR1 180–250 mg/dL, TAR2 >250 mg/dL.

  • CV, coefficient of variation; GMI, glucose management indicator; SDglu, glucose SD; TAR, time above range; TBR, time below range; TIR, time in range.