K1 values (in mL ccm−1 min−1) derived from 68Ga-DOTA uptake after adjustment of the distribution to a 1-tissue compartment model
| Lean | Obese | |
| Pancreas | 1.57±0.67 | 0.14±0.05* |
| Duodenum | 0.14±0.02 | 0.40±0.21* |
| Subcutaneous fat | 0.08±0.03 | 0.01±0.01* |
| Visceral fat | 0.02±0.01 | 0.03±0.01 |
K1 values were representative for the tissue perfusion and indicated a reduced flow for the pancreas and the subcutaneous fat in the obese animals while there was an increase in the duodenal area.
*p<0.05.