Sensitivity analysis showing associations with TMAO (μmol/L) when MVPA and sedentary time were mutually adjusted
| Covariate | Coefficient per 30 min (95% CI) | Coefficient per SD (95% CI) | P value | Participants (n) | Observations included (n) |
| MVPA | −0.561 (−1.119 to −0.004) | −0.438 (−0.003 to 0.873) | 0.048 | 449 | 738 |
| Sedentary time | 0.017 (−0.168 to 0.202) | 0.059 (−0.575 to 0.692) | 0.933 | 449 | 738 |
Model mutually adjusted for MVPA and sedentary time along with age, sex, ethnicity, time, smoking status, randomization group, accelerometer wear time, kidney function, high-density lipoprotein (HDL) cholesterol, triglycerides, body mass index (BMI), systolic blood pressure, HbA1c, lipid-lowering medication, blood pressure-lowering medication, meat intake, and fish intake.
MVPA, moderate to vigorous physical activity; TMAO, trimethylamine N-oxide.