Association of expression of the circulating lncRNA NKILA with different parameters among patients with T2DM
| Variable | Fold change in NKILA expression among subjects with T2DM (mean±SD) | P value |
| Overall expression | 3.94±3.07 | – |
| Age (years) | ||
| ≤40 years | 3.40±3.19 | 0.05 |
| >40 years | 3.99±3.01 | |
| Sex | ||
| Male | 3.90±3.13 | 0.71 |
| Female | 3.99±3.01 | |
| Hypertension | ||
| Yes | 4.57±3.27 | 0.001 |
| No | 2.96±2.44 | |
| Nephropathy | ||
| Yes | 3.95±3.36 | 0.63 |
| No | 3.93±2.79 | |
| Weight loss | ||
| Yes | 3.63±2.87 | 0.19 |
| No | 4.23±3.23 | |
| Fatigue | ||
| Yes | 3.92±2.58 | 0.86 |
| No | 3.96±3.17 | |
| Slow wound healing | ||
| Yes | 3.81±3.09 | 0.30 |
| No | 4.13±3.05 | |
| Retinopathy | ||
| Yes | 4.47±3.40 | 0.12 |
| No | 3.68±2.87 | |
| Loss of appetite | ||
| Yes | 4.02±3.26 | 0.98 |
| No | 3.86±2.84 | |
| Smoking | ||
| Yes | 5.28±3.03 | <0.0001 |
| No | 2.81±2.63 | |
| Alcoholism | ||
| Yes | 5.87±2.82 | <0.0001 |
| No | 1.94±1.78 | |
lncRNA, long non-coding RNA; NKILA, NF-kappaB interacting lncRNA; T2DM, type 2 diabetes mellitus.