Table 2

Pancreatic exocrine function and selected nutritional indexes, by group

ControlsNew-onset T1DLong-standing T1DP value
N251219
Lipase activity (%)121.3 (93.7–175.5)118.8 (88.8–143.0)116.7 (87.4–141.4)0.4893
Fecal elastase (µg/g)500 (500–500)474 (353.5–500)380 (281–500)0.0020§
Total amylase (U/L)65 (54–76)63 (35–86)50 (39–74)0.1293
Pancreatic amylase (U/L)28 (23–35)25 (14–41)18 (14–21)0.0013¶
Lipase (U/L)30 (25–33)26 (21–39)22 (19–26)0.0106*
Retinol binding protein (g/L)0.042 (0.035–0.047)0.037 (0.035–0.042)0.031 (0.025–0.034)0.0002†
Prealbumin (g/L)0.28 (0.24–0.32)0.26 (0.25–0.29)0.20 (0.18–0.22)0.0001‡

  • Continuous variables are presented as median and IQR in parentheses; categorical variables are presented as frequency and per cent in parentheses.

  • *P=0.5482: new-onset T1D versus controls; p=0.0019: long-standing T1D versus controls; p=0.1149: new-onset T1D versus long-standing T1D (test for trend: p=0.037).

  • †P=0.4062: new-onset T1D versus controls; p=0.0001: long-standing T1D versus controls; p=0.0042: new-onset T1D versus long-standing T1D (test for trend: p=0.002).

  • ‡P=0.5761: new-onset T1D versus controls; p<0.0001: long-standing T1D versus controls; p=0.0001: new-onset T1D versus long-standing T1D (test for trend: p<0.0001).

  • §P=0.0070: new-onset T1D versus controls; p=0.0010: long-standing T1D versus controls; p=0.2362: new-onset T1D versus long-standing T1D (test for trend: p=0.199).

  • ¶P=0.5203: new-onset T1D versus controls; p=0.0001: long-standing T1D versus controls; p=0.1825: new-onset T1D versus long-standing T1D (test for trend: p=0.014).

  • T1D, type 1 diabetes.