Table 1

Baseline characteristics stratified by tertile according to T50

Overall
(N=932)
Tertile 1
(<235 min)
(N=311)
Tertile 2
(235–293 min)
(N=310)
Tertile 3
(>293 min)
(N=311)
Age (years)65.8 (58.5–72.0)65.7 (57.9–71.7)65.7 (59.7–72.3)65.9 (58.7–71.7)
Sex, % male (n)54.7 (510)44.7 (139)53.9 (167)65.6 (204)
Smoking, % current (n)17.0 (157)23.7 (73)15.2 (47)12.0 (37)
Alcohol use, % (n)36.1 (273)30.1 (78)38.2 (91)40.2 (104)
BMI (kg/m²)29.3 (26.7–33.0)29.7 (27.1–33.4)29.1 (26.4–32.8)29.1 (26.7–32.7)
SBP (mm Hg)135 (125-144)136 (124-145)135 (125-144)134 (125-141)
DBP (mm Hg)80 (70-83)80 (72-84)76 (70-82)80 (72-82)
Duration of diabetes (years)6.5 (3.0–10.2)6.7 (3.2–10.5)7.2 (2.9–10.5)5.9 (2.79.7)
HbA1c (mmol/mol)49 (44-54)50 (45-55)49 (43-54)48 (44-53)
Total cholesterol (mmol/L)4.3 (3.7–4.9)4.2 (3.7–4.9)4.3 (3.7–4.9)4.3 (3.7–4.8)
HDL cholesterol (mmol/L)1.2 (1.0–1.5)1.3 (1.0–1.5)1.2 (1.1–1.5)1.2 (1.0–1.4)
Total cholesterol/HDL ratio3.4 (2.8–4.2)3.3 (2.7–4.3)3.4 (2.8–4.1)3.5 (2.9–4.3)
LDL cholesterol (mmol/L)2.3 (1.8–2.8)2.2 (1.7–2.8)2.4 (1.8–2.8)2.3 (1.9–2.9)
Triglycerides (mmol/L)1.5 (1.1–2.0)1.5 (1.1–2.1)1.4 (1.0–2.0)1.5 (1.0–2.1)
History of macrovascular event, % (n)25.1 (234)25.4 (79)23.5 (73)26.4 (82)
History of AP, % (n)7.4 (59)5.8 (18)7.1 (22)9.3 (29)
History of MI, % (n)8.6 (80)9.6 (30)5.8 (18)10.3 (32)
History of PCI, % (n)2.6 (24)3.5 (11)2.3 (7)1.9 (6)
History of CABG, % (n)4.9 (46)5.5 (17)4.8 (15)4.5 (14)
History of TIA, % (n)3.3 (31)1.6 (5)4.5 (14)3.9 (12)
History of stroke, % (n)6.1 (57)5.5 (17)7.4 (23)5.5 (17)
History of microvascular event, % (n)35.2 (293)35.4 (97)35.3 (97)34.9 (99)
History of retinopathy, % (n)4.6 (38)7.3 (20)2.2 (6)4.3 (12)
History of peripheral neuropathy, % (n)19.7 (171)18.5 (53)20.7 (60)19.7 (58)
History of albuminuria, % (n)13.7 (128)13.8 (43)13.5 (42)13.8 (43)
eGFR, mL/min/1.73 m²74 (61-86)73 (60-89)73 (61-85)75 (63-87)
Albumin/creatinin ratio0.8 (0.4–1.5)0.7 (0.4–1.5)0.8 (0.4–1.5)1.0 (0.4–1.5)
Diet, % (n)19.4 (181)17.2 (53)19.0 (59)22.2 (69)
Oral glucose lowering drugs, % (n)78.1 (728)79.4 (247)79.0 (245)75.9 (236)
Insulin therapy, % (n)13.0 (121)16.4 (51)12.3 (38)10.3 (32)
Cholesterol-lowering drugs, % (n)79.6 (741)77.2 (240)82.3 (255)79.4 (246)
Antihypertensive therapy, % (n)84.7 (788)84.8 (263)85.2 (264)84.2 (261)
  • Data are presented as percentage (number), mean (SD) or median (IQR).

  • AP, angina pectoris; BMI, body mass index; CABG, coronary artery bypass grafting; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MI, myocardial infarction; PCI, percutaneous coronary intervention; SBP, systolic blood pressure; TIA, transient ischemic attack.