Pearson correlations of apoA2, apoC1, apoC3 and apoE with demographic, biochemical data from combined cohort (control women and women with GDM)
apoA2 | apoC1 | apoC3 | apoE | CRP | ||||||
r | P value | r | P value | r | P value | r | P value | r | P value | |
BMI | −0.192 | 0.117 | −0.053 | 0.666 | 0.134 | 0.278 | −0.043 | 0.728 | 0.123 | 0.318 |
SBP baseline (mm Hg) | −0.088 | 0.474 | −0.028 | 0.818 | 0.074 | 0.550 | −0.021 | 0.865 | 0.029 | 0.813 |
DBP baseline (mm Hg) | 0.174 | 0.156 | 0.010 | 0.937 | −0.073 | 0.552 | −0.119 | 0.334 | −0.052 | 0.671 |
HOMA-IR | −0.204 | 0.239 | 0.013 | 0.940 | −0.008 | 0.964 | 0.095 | 0.586 | 0.025 | 0.887 |
Gestational age at GDM diagnosis (weeks) | −0.081 | 0.512 | 0.132 | 0.281 | 0.330* | 0.006 | 0.109 | 0.375 | 0.115 | 0.349 |
Cholesterol (mmol/L) | 0.100 | 0.539 | 0.003 | 0.984 | 0.086 | 0.598 | 0.016 | 0.920 | 0.072 | 0.659 |
Triglycerides (mmol/L) | −0.175 | 0.280 | −0.219 | 0.168 | 0.029 | 0.861 | −0.192 | 0.236 | −0.037 | 0.822 |
High-density lipoprotein (mmol/L) | 0.003 | 0.985 | 0.201 | 0.214 | 0.077 | 0.641 | 0.175 | 0.287 | 0.106 | 0.519 |
Low-density lipoprotein (mmol/L) | 0.111 | 0.509 | −0.035 | 0.831 | 0.060 | 0.720 | 0.060 | 0.719 | 0.081 | 0.627 |
CRP (mg/mL) | −0.268* | 0.027 | −0.056 | 0.649 | −0.247*† | 0.042 | −0.119 | 0.334 | 1.000 | |
Second-term SBP (mm Hg) | −0.143 | 0.256 | −0.025 | 0.842 | 0.019 | 0.882 | 0.135 | 0.285 | −0.230 | 0.066 |
Second-term DBP (mm Hg) | −0.003 | 0.983 | 0.053 | 0.677 | 0.040 | 0.750 | −0.127 | 0.312 | 0.041 | 0.746 |
Weight at delivery (kg) | −0.023 | 0.856 | −0.050 | 0.692 | 0.152 | 0.228 | 0.021 | 0.869 | 0.088 | 0.486 |
Gestational age at delivery (weeks) | 0.390* | 0.001 | −0.058 | 0.645 | −0.002 | 0.986 | 0.013 | 0.917 | −0.078 | 0.537 |
Baby weight (g) | 0.134 | 0.300 | 0.019 | 0.886 | 0.067 | 0.603 | 0.093 | 0.474 | 0.043 | 0.742 |
apoA1 (mg/mL) | 0.264*† | 0.030 | 0.536* | 0.000 | 0.217 | 0.075 | 0.219 | 0.073 | 0.094 | 0.444 |
apoA2 (mg/mL) | 1.000 | 0.319* | 0.008 | 0.574* | 0.000 | 0.497* | 0.000 | −0.268*† | 0.027 | |
apoB (mg/mL) | −0.092 | 0.456 | 0.346* | 0.004 | −0.218 | 0.075 | 0.139 | 0.258 | 0.399* | 0.001 |
apoC1 (mg/mL) | 0.319* | 0.008 | 1.000 | 0.353* | 0.003 | 0.562* | 0.000 | −0.056 | 0.649 | |
apoC3 (mg/mL) | 0.574* | 0.000 | 0.353* | 0.003 | 1.000 | 0.714* | 0.000 | −0.247*† | 0.042 | |
apoD (mg/mL) | −0.189 | 0.123 | 0.221 | 0.070 | −0.496* | 0.000 | −0.313* | 0.009 | 0.236 | 0.053 |
apoE (mg/mL) | 0.497* | 0.000 | 0.562* | 0.000 | 0.714* | 0.000 | 1.000 | −0.119 | 0.334 | |
apoH (mg/mL) | −0.290*† | 0.016 | 0.073 | 0.552 | −0.382* | 0.001 | −0.203 | 0.097 | 0.379* | 0.001 |
apoJ (mg/mL) | 0.000 | 1.000 | 0.068 | 0.582 | −0.108 | 0.378 | −0.100 | 0.415 | 0.199 | 0.104 |
*Correlation is significant at the 0.01 level (two-tailed).
†Correlation is significant at the 0.05 level (two-tailed).
apo, apolipoprotein; BMI, Body Mass Index; CRP, C reactive protein; DBP, diastolic blood pressure; GDM, gestational diabetes mellitus; HOMA-IR, Homeostatic Model Assessment for Insulin Resistance; SBP, systolic blood pressure.