Table 1

Maternal (24–28 weeks of gestation) and cord plasma concentrations of triglycerides, HDL, LDL, OxLDL, and OxLDL to LDL ratio and surrogate indices of insulin sensitivity and beta-cell function in newborns in a singleton birth cohort (N=248)

Maternal plasmaCord plasmaP value*
BiomarkerMedianMean±SEMedianMean±SE
Triglycerides, mmol/L2.152.22±0.050.350.43±0.02<0.001
HDL, mmol/L1.941.98±0.030.640.70±0.02<0.001
LDL, mmol/L3.083.21±0.060.730.80±0.03<0.001
OxLDL, U/L1434.81815.5±112.7556.4905.5±84.7<0.001
OxLDL:LDL, U/mmol468.9591.4±29.2790.71278.0±141.2<0.001
Glucose, mmol/L4.574.64±0.06
Insulin, pmol/L27.236.7±2.4
Glucose:insulin ratio (mmol:pmol)0.160.23±0.01
Proinsulin:insulin ratio (pmol:pmol)0.560.74±0.06
  • Glucose 1 mmol/L=18 mg/dL; insulin 1 mU/L=6 pmol/L.

  • *P values in t-tests for differences in cord versus maternal plasma concentrations in log-transformed data.

  • HDL, high-density lipoprotein; LDL, low-density lipoprotein; OxLDL, oxidized low-density lipoprotein.