Relative intensities of four significantly changed metabolites between the fetal-exposed and non-exposed groups in both 2014 and 2019
2014 | 2019 | |||||
Fetal-exposed (1959–1962) | Non-exposed (1963–1965) | P value | Fetal-exposed (1959–1962) | Non-exposed (1963–1965) | P value | |
n | 82 | 79 | 97 | 94 | ||
Age, years | 53.1±0.9 | 50.3±0.8 | <0.001 | 58.0±0.9 | 55.3±0.8 | <0.001 |
Men, % | 37.87 | 35.4 | 0.756 | 35.1 | 39.4 | 0.538 |
Diabetes, % | 11.0 | 6.3 | 0.296 | 20.6 | 7.4 | 0.009 |
BMI, kg/m2 | 25.3±3.6 | 23.8±2.7 | 0.003 | 24.8±4.1 | 24.4±2.6 | 0.456 |
Indole-3-carbinol | 8.8±2.8 | 10.0±3.0 | 0.009 | 6.0±1.4 | 6.4±1.5 | 0.039 |
PC(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/16:1(9Z)) | 13.9±11.2 | 19.6±14.6 | 0.006 | 5.2±2.7 | 6.1±3.2 | 0.047 |
Pyrimidine | 1.4±0.6 | 1.7±0.6 | 0.006 | 0.51±0.31 | 0.61±0.33 | 0.028 |
PC(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z)) | 0.57±0.42 | 0.80±0.56 | 0.004 | 0.23±0.12 | 0.27±0.14 | 0.016 |
Continuous variables are expressed as mean±SD and categorical variables are described as percentage.
Student’s t-test was used for continuous variables and Pearson’s χ2 test was used for categorical variables.
BMI, body mass index; PC, phosphatidylcholine.