Table 3

Relative intensities of four significantly changed metabolites between the fetal-exposed and non-exposed groups in both 2014 and 2019

	2014			2019
	Fetal-exposed (1959–1962)	Non-exposed (1963–1965)	P value	Fetal-exposed (1959–1962)	Non-exposed (1963–1965)	P value
n	82	79		97	94
Age, years	53.1±0.9	50.3±0.8	<0.001	58.0±0.9	55.3±0.8	<0.001
Men, %	37.87	35.4	0.756	35.1	39.4	0.538
Diabetes, %	11.0	6.3	0.296	20.6	7.4	0.009
BMI, kg/m²	25.3±3.6	23.8±2.7	0.003	24.8±4.1	24.4±2.6	0.456
Indole-3-carbinol	8.8±2.8	10.0±3.0	0.009	6.0±1.4	6.4±1.5	0.039
PC(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/16:1(9Z))	13.9±11.2	19.6±14.6	0.006	5.2±2.7	6.1±3.2	0.047
Pyrimidine	1.4±0.6	1.7±0.6	0.006	0.51±0.31	0.61±0.33	0.028
PC(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z))	0.57±0.42	0.80±0.56	0.004	0.23±0.12	0.27±0.14	0.016

Continuous variables are expressed as mean±SD and categorical variables are described as percentage.
Student’s t-test was used for continuous variables and Pearson’s χ² test was used for categorical variables.
BMI, body mass index; PC, phosphatidylcholine.