HRs and 95% CI for mortality and graft failure in US transplant recipients (2000–2018), by diabetes and donor status
Total | Living donor | Deceased donor | ||||
Unadjusted HR | Adjusted HR* | Unadjusted HR | Adjusted HR* | Unadjusted HR | Adjusted HR* | |
Mortality | ||||||
No diabetes | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | |||
T1D | 1.35 (1.32 to 1.39) | 1.95 (1.88 to 2.03) | 1.90 (1.81 to 2.00) | 2.04 (1.91 to 2.17) | 1.12 (1.08 to 1.15) | 1.91 (1.82 to 2.00) |
T2D | 2.26 (2.22 to 2.29) | 1.65 (1.62 to 1.69) | 2.81 (2.72 to 2.90) | 1.74 (1.67 to 1.82) | 1.96 (1.92 to 1.99) | 1.62 (1.59 to 1.66) |
Graft failure | ||||||
No diabetes | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | |||
T1D | 1.08 (1.04 to 1.11) | 1.24 (1.18 to 1.31) | 1.36 (1.27 to 1.46) | 1.30 (1.19 to 1.42) | 0.92 (0.88 to 0.96) | 1.22 (1.14 to 1.30) |
T2D | 1.38 (1.35 to 1.41) | 1.32 (1.28 to 1.36) | 1.53 (1.46 to 1.60) | 1.51 (1.41 to 1.60) | 1.24 (1.21 to 1.27) | 1.27 (1.23 to 1.31) |
*Adjusted for recipient characteristics of age, sex, race/ethnicity, insurance status, ESKD duration prior to transplant, smoking history, BMI, comorbidities, and graft failure status (where appropriate), as well as donor characteristics of age, sex, race/ethnicity, cold ischemic time, and donor risk level.
BMI, body mass index; ESKD, end-stage kidney disease; T1D, type 1 diabetes; T2D, type 2 diabetes.