Characteristics among US transplant recipients at the time of kidney transplant, by primary cause of ESKD
| Total | Cause of ESKD | P value‡ | |||
| T1D | T2D | Non-diabetes | |||
| Patient characteristics | |||||
| N (%) | 254 188 (100.0) | 20 346 (8.0) | 59 405 (23.4) | 174 437 (68.6) | |
| Sex, male (%) | 61.2 | 59.4 | 66.7 | 59.5 | <0.001 |
| Age, mean (SD) | 51.8 (13.2) | 45.1 (10.8) | 57.7 (9.9) | 50.6 (13.7) | <0.001 |
| Race (%) | |||||
| Non-Hispanic white | 52.8 | 69.6 | 43.5 | 54.0 | <0.001 |
| Non-Hispanic black | 24.7 | 16.4 | 26.4 | 25.1 | |
| Hispanic | 15.8 | 11.2 | 21.9 | 14.2 | |
| Other | 6.7 | 2.8 | 8.2 | 6.7 | |
| ESKD duration*, mean (SD) | 2.9 (3.0) | 2.1 (2.3) | 3.1 (2.5) | 3.0 (3.2) | <0.001 |
| Transplant year (%) | |||||
| 2000–2005 | 22.7 | 30.2 | 20.8 | 22.5 | <0.001 |
| 2006–2010 | 32.7 | 33.7 | 33 | 32.4 | |
| 2011–2018 | 44.6 | 36.2 | 46.2 | 45.1 | |
| Health insurance status (%) | |||||
| Medicare | 56.5 | 52.7 | 64.5 | 54.2 | <0.001 |
| Medicaid | 4.4 | 4.3 | 3.7 | 4.7 | |
| Private | 37.8 | 42.0 | 30.2 | 39.6 | |
| Other | 1.5 | 1.1 | 1.6 | 1.6 | |
| BMI (kg/m2), mean (SD) | 28.1 (6.6) | 26.7 (5.7) | 29.8 (6.5) | 27.7 (6.6) | <0.001 |
| History of smoking (%) | 10.6 | 9.4 | 10.3 | 10.9 | <0.001 |
| Comorbidities† | |||||
| CHF (%) | 12.1 | 12.6 | 20.5 | 9.0 | <0.001 |
| Stroke (%) | 3.5 | 3.9 | 5.4 | 2.7 | <0.001 |
| COPD (%) | 2.8 | 1.6 | 3.2 | 2.8 | <0.001 |
| PVD (%) | 4.5 | 8.3 | 9.5 | 2.3 | <0.001 |
| Cancer (%) | 2.4 | 0.8 | 1.8 | 2.8 | <0.001 |
| Donor characteristics | |||||
| Age, mean (SD) | 39.4 (15.1) | 33.8 (14.3) | 40.9 (15.4) | 39.5 (15.0) | <0.001 |
| Sex, male (%) | 52.7 | 58.1 | 53.1 | 51.9 | <0.001 |
| Race (%) | |||||
| Non-Hispanic white | 69.1 | 72.2 | 66.4 | 69.7 | <0.001 |
| Non-Hispanic black | 13.3 | 12.9 | 13.7 | 13.1 | |
| Hispanic | 13.9 | 12.3 | 15.8 | 13.4 | |
| Other | 3.8 | 2.6 | 4.1 | 3.8 | |
| Cold ischemic time, hours Median (25th–75th percentile) | 12.0 (2.0–20.0) | 10.0 (1.4–18.7) | 14.0 (4.8–21.0) | 11.6 (2.0–19.4) | <0.001 |
| Donor risk level (%)† | |||||
| LD | 36.9 | 47.9 | 29.4 | 38.5 | <0.001 |
| Low DD risk | 12.9 | 11.3 | 11.0 | 13.6 | |
| Moderate DD risk | 42.7 | 36.0 | 48.5 | 41.4 | |
| High DD risk | 7.5 | 4.8 | 11.1 | 6.5 | |
| Simultaneous kidney/pancreas (%) | 5.4 | 43.4 | 6.8 | 0.5 | <0.001 |
KDPI is estimated among DD only and is defined as low risk (KDPI=0–20), moderate risk (KDPI >20–85) or high risk (KDPI >85).
*ESKD duration prior to transplant date.
†High-risk donor is defined using KDPI.
‡P value for difference between groups with T1D, T2D and without diabetes.
BMI, body mass index; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; DD, deceased donor; ESKD, end-stage kidney disease; KDPI, Kidney Donor Profile Index; LD, living donor; PVD, peripheral vascular disease; T1D, type 1 diabetes; T2D, type 2 diabetes.