Table 3

Evidence attributes of the identified variants of monogenic diabetes

Gene	Variant	PVS1	PS1-5	PM1	PM2	PM3	PM4	PM5	PM6	PP1	PP2	PP3	PP4	PP5	Final
ABCC8	c.1801G>A			+	+							+			US
ABCC8	c.307C>T				+							+			US
PDX1	c.97C>G				+			+				+			US
INS-IGF2	c.53G>A			+	+						+				US
PAX4	c.491G>A			+	+							+			US
HNF1A	c.1630G>A				+									+	US

US, uncertain significance.