Table 3

Evidence attributes of the identified variants of monogenic diabetes

GeneVariantPVS1PS1-5PM1PM2PM3PM4PM5PM6PP1PP2PP3PP4PP5Final
ABCC8c.1801G>A+++US
ABCC8c.307C>T++US
PDX1c.97C>G+++US
INS-IGF2c.53G>A+++US
PAX4c.491G>A+++US
HNF1Ac.1630G>A++US
  • US, uncertain significance.