No diabetic complications (0) | DR or CKD (1) | DR and CKD (2) | P value | ||||||
Characteristics | (N=987) | (N=677) | (N=146) | Three groups | (1) versus (0) | (2) versus (0) | |||
Age (years) | 59.7 | 9.6 | 62.7 | 9.8 | 65.6 | 7.9 | <0.001 | <0.001 | <0.001 |
Ethnicity | <0.001 | <0.001 | <0.001 | ||||||
Malay | 265 | 26.9% | 257 | 37.9% | 77 | 52.7% | |||
Indian | 474 | 48.0% | 299 | 44.2% | 52 | 35.6% | |||
Chinese | 248 | 25.1% | 121 | 17.9% | 17 | 11.6% | |||
Men | 465 | 47.1% | 336 | 49.6% | 57 | 39.0% | 0.065 | 0.313 | 0.068 |
BMI (kg/m2) | 26.9 | 4.6 | 26.4 | 4.5 | 27.1 | 4.9 | 0.112 | 0.061 | 0.619 |
Systolic BP (mm Hg) | 141.4 | 19.3 | 149.5 | 23.5 | 158.5 | 24 | <0.001 | <0.001 | <0.001 |
Diastolic BP (mm Hg) | 77.9 | 9.4 | 78.6 | 10.9 | 78.4 | 11.8 | 0.468 | 0.222 | 0.544 |
HbA1c (%) | 7.8 | 1.8 | 8.2 | 1.9 | 8.3 | 1.9 | <0.001 | <0.001 | 0.007 |
Total cholesterol (mmol/L) | 5.1 | 1.4 | 5.2 | 1.3 | 1.3 | 1.5 | 0.099 | 0.439 | 0.026 |
HDL (mmol/L) | 1.2 | 0.3 | 1.2 | 0.3 | 1.2 | 0.4 | 0.170 | 0.192 | 0.121 |
LDL (mmol/L) | 3.2 | 1.0 | 3.1 | 1.0 | 3.1 | 1.1 | 0.506 | 0.299 | 0.437 |
Blood glucose (mmol/L) | 10.3 | 4.6 | 11.2 | 5.6 | 11.1 | 5.7 | 0.002 | 0.001 | 0.080 |
Duration of diabetes (years) | 6.1 | 7.2 | 10.3 | 9.4 | 13.5 | 9.9 | <0.001 | <0.001 | <0.001 |
Therapy for diabetes | <0.001 | <0.001 | <0.001 | ||||||
Diet only | 70 | 8.7% | 24 | 3.9% | 4 | 2.9% | |||
Insulin only | 0 | 0% | 6 | 1.0% | 2 | 1.4% | |||
Oral medication only | 384 | 47.5% | 287 | 46.6% | 65 | 46.4% | |||
Oral medication and insulin | 20 | 2.5% | 47 | 7.6% | 21 | 15.0% | |||
Hypertension | 687 | 69.8% | 558 | 82.4% | 139 | 95.2% | <0.001 | <0.001 | <0.001 |
Hyperlipidaemia | 567 | 58.6% | 377 | 57.7% | 94 | 64.8% | 0.279 | 0.710 | 0.153 |
Current smoking | 146 | 14.8% | 74 | 11.0% | 9 | 6.1% | 0.003 | 0.024 | 0.005 |
Current alcohol | 78 | 7.9% | 50 | 7.4% | 2 | 1.4% | 0.016 | 0.720 | 0.004 |
Estimated GFR, mL/min/1.73m2 | 88.7 | 14.6 | 75.7 | 25.3 | 42.4 | 13.9 | <0.001 | <0.001 | <0.001 |
Albumin:creatinine ratio | 48.6 | 134.5 | 191.2 | 685.8 | 1028.5 | 3704.4 | <0.001 | <0.001 | <0.001 |
Data presented are mean and SD, or count and proportion for continuous and categorical variables respectively.
BMI, body mass index; GFR, glomerular filtration rate.