Associations between 2-hour plasma glucose during the 75 g oral glucose tolerance test (OGTT) and all-cause mortality in NHANES 2005–2014 followed through 2015
| Exposures | Event N/ total N | Adjusted HRs (95% CI) of all-cause mortality | ||
| Age and sex | Model 1* | Model 2† | ||
| 2-hour plasma glucose during OGTT (per 10 mg/dL increase) | 507/8795 | 1.04 (1.02 to 1.05) | 1.03 (1.02 to 1.05) | 1.03 (1.01 to 1.05) |
| Categories based on 2-hour plasma glucose during the 75 g OGTT | ||||
| Normal glucose tolerance | 253/6754 | Reference | Reference | Reference |
| Impaired glucose tolerance | 148/1471 | 1.23 (0.93 to 1.62) | 1.21 (0.92 to 1.59) | 1.19 (0.90 to 1.59) |
| Diabetes | 106/570 | 2.13 (1.62 to 2.79) | 1.98 (1.49 to 2.63) | 1.93 (1.41 to 2.64) |
| P for trend | <0.001 | <0.001 | <0.001 | |
*HR adjusted for age, sex, race/ethnicity, education status, marital status, and smoking.
†HR adjusted for BMI, eGFR, history of cancer, cardiovascular disease, stroke, hypertension, statin prescription in addition to covariates in model 1.
BMI, body mass index; eGFR, estimated glomerular filtration rate; NHANES, National Health and Nutrition Examination Survey.