Table 2

Characteristics of standard and data-derived BMI and waist cut-offs for detection of hyperglycemia, based on the American Diabetes Association categories

AUCSensitivity (%)Specificity (%)PPV (%)NPV (%)Youden index
BMI ≥25 kg/m2
 Women57.1 (52.5 to 61.7)79.0 (73.0 to 85.0)35.0 (28.0 to 43.0)68.0 (63.0 to 73.0)49.0 (40.0 to 59.0)0.14
 Men59.4 (52.6 to 66.2)64.0 (54.0 to 73.0)54.0 (44.0 to 64.0)63.0 (54.0 to 70.0)56.0 (45.0 to 67.0)0.19
BMI ≥30 kg/m2
 Women57.6 (52.3 to 63.0)48.0 (42.0 to 54.0)67.0 (58.0 to 75.0)72.0 (64.0 to 78.0)43.0 (36.0 to 49.0)0.15
 Men58.1 (52.4 to 63.8)30.0 (22.0 to 38.0)86.0 (77.0 to 92.0)72.0 (57.0 to 84.0)51.0 (42.0 to 59.0)0.16
BMI (data-derived)
 Women (≥27 kg/m2)57.8 (52.4 to 63.2)63.0 (56.0 to 69.0)53.0 (44.0 to 61.0)70.0 (64.0 to 75.0)45.0 (37.0 to 53.0)0.16
 Men (≥24 kg/m2)61.9 (55.9 to 67.8)72.0 (64.0 to 79.0)51.0 (41.0 to 61.0)64.0 (56.0 to 71.0)61.0 (50.0 to 71.0)0.24
Abdominal obesity (IDF)
 Women (WC ≥80 cm)61.7 (57.3 to 66.1)89.0 (84.0 to 92.0)35.0 (27.0 to 44.0)70.0 (66.0 to 74.0)64.0 (52.0 to 74.0)0.24
 Men (WC ≥94 cm)62.3 (55.9 to 68.8)46.0 (37.0 to 56.0)79.0 (67.0 to 87.0)72.0 (61.0 to 81.0)55.0 (45.0 to 64.0)0.25
Abdominal obesity (AHA/NHLBI)
 Women (WC ≥88 cm)62.9 (57.6 to 68.2)68.0 (62.0 to 74.0)58.0 (50.0 to 65.0)74.0 (68.0 to 79.0)51.0 (43.0 to 59.0)0.26
 Men (WC ≥102 cm)57.7 (52.8 to 62.7)25.0 (18.0 to 33.0)90.0 (83.0 to 95.0)76.0 (59.0 to 87.0)50.0 (42.0 to 58.0)0.16
Abdominal obesity (data-derived)
 Women (WC ≥87 cm)63.7 (58.3 to 69.1)71.0 (65.0 to 77.0)56.0 (47.0 to 64.0)74.0 (68.0 to 79.0)53.0 (44.0 to 61.0)0.28
 Men (WC ≥86 cm)66.2 (59.9 to 72.6)74.0 (65.0 to 81.0)59.0 (48.0 to 69.0)68.0 (60.0 to 75.0)65.0 (54.0 to 76.0)0.34
  • Relevant findings using WHO categories of hyperglycemia are described in the text.

  • AHA, American Heart Association; AUC, area under the curve; BMI, body mass index; IDF, International Diabetes Federation; NHLBI, National Heart, Lung, and Blood Institute; NPV, negative predictive value; PPV, positive predictive value; WC, waist circumference.