Remaining lifetime risks vs 10-year risks of first incident cardiovascular disease by glycemic status among women and men
| Normoglycemia | Impaired fasting glucose | Type 2 diabetes | |||||
| Cumulative incidence, % (95% CI) | Cumulative incidence, % (95% CI) | Cumulative incidence, % (95% CI) | |||||
| Women (n=4468) | Men (n=2753) | Women (n=634) | Men (n=570) | Women (n=596) | Men (n=480) | ||
| CVD | |||||||
| N events | 740 | 608 | 149 | 147 | 182 | 155 | |
| Age 55 | 10 years | 47.7 (44.3 to 51.1) | 53.9 (50.1 to 57.7) | 47.2 (39.9 to 54.4) | 56.5 (49.0 to 64.0) | 65.3 (58.6 to 72.1) | 63.8 (56.9 to 70.7) |
| Lifetime | 52.7 (49.5 to 55.9) | 59.1 (55.5 to 62.7) | 55.1 (48.3 to 61.9) | 62.1 (55.2 to 69.1) | 61.5 (54.7 to 68.3) | 60.3 (53.1 to 67.5) | |
| Age 65 | 10 years | 46.6 (43.1 to 50.1) | 47.5 (43.3 to 51.8) | 45.9 (38.5 to 53.3) | 52.5 (44.6 to 60.4) | 63.7 (57.3 to 70.1) | 57.5 (50.1 to 64.9) |
| Lifetime | 52.4 (49.2 to 55.7) | 55.5 (51.7 to 59.4) | 49.9 (48.1 to 61.8) | 59.4 (52.1 to 66.7) | 61.4 (54.8 to 67.9) | 56.4 (48.9 to 63.9) | |
| Age 75 | 10 years | 43.2 (39.2 to 47.2) | 39.7 (34.4 to 45.0) | 43.0 (34.3 to 51.7) | 46.9 (37.0 to 56.7) | 58.8 (51.7 to 66.0) | 50.2 (41.0 to 59.3) |
| Lifetime | 50.8 (47.1 to 54.5) | 51.3 (46.5 to 56.0) | 53.6 (45.5 to 61.7) | 56.0 (47.0 to 65.1) | 58.1 (50.9 to 65.4) | 51.1 (42.0 to 60.3) | |
| Age 85 | 10 years | 37.4 (32.1 to 42.7) | 32.8 (23.7 to 41.8) | 34.2 (22.9 to 45.4) | 36.6 (20.0 to 53.2) | 45.9 (35.3 to 56.5) | 44.9 (29.0 to 60.8) |
| Lifetime | 43.9 (38.8 to 49.0) | 48.1 (39.9 to 56.3) | 49.7 (39.3 to 60.2) | 46.0 (29.7 to 62.4) | 47.9 (37.5 to 58.4) | 45.6 (29.0 to 62.2) | |
| CHD | |||||||
| N events | 238 | 328 | 50 | 65 | 64 | 70 | |
| Age 55 | 10 years | 16.8 (14.4 to 19.2) | 29.3 (26.2 to 32.5) | 15.1 (10.4 to 19.7) | 25.9 (19.4 to 32.3) | 28.7 (22.2 to 35.1) | 34.7 (27.8 to 41.6) |
| Lifetime | 18.8 (16.4 to 21.2) | 33.3 (29.9 to 36.6) | 18.0 (12.8 to 23.1) | 30.2 (23.7 to 36.6) | 24.0 (18.0 to 30.2) | 30.9 (24.2 to 37.6) | |
| Age 65 | 10 years | 15.5 (13.1 to 17.9) | 21.1 (18.2 to 24.1) | 13.4 (9.1 to 17.8) | 18.9 (13.3 to 24.6) | 25.0 (19.3 to 30.8) | 27.9 (21.6 to 34.3) |
| Lifetime | 18.0 (15.6 to 20.4) | 27.5 (24.2 to 30.8) | 17.6 (12.5 to 22.7) | 24.6 (18.7 to 30.6) | 21.0 (15.6 to 26.4) | 27.1 (20.7 to 33.4) | |
| Age 75 | 10 years | 12.5 (10.0 to 15.0) | 13.1 (10.1 to 16.0) | 10.4 (6.2 to 14.7) | 11.3 (5.8 to 16.9) | 19.2 (13.8 to 24.6) | 20.8 (14.3 to 27.4) |
| Lifetime | 15.7 (13.2 to 18.3) | 21.2 (17.5 to 24.8) | 14.3 (9.0 to 19.6) | 18.9 (12.6 to 25.1) | 18.0 (12.7 to 23.3) | 22.2 (15.5 to 29.0) | |
| Age 85 | 10 years | 9.9 (7.0 to 12.9) | 8.0 (4.1 to 12.0) | 3.2 (0.1 to 6.3) | 6.9 (0.3 to 13.5) | 12.6 (6.6 to 18.6) | 10.4 (2.4 to 18.3) |
| Lifetime | 11.8 (8.9 to 14.8) | 16.1 (10.8 to 21.5) | 11.1 (5.1 to 17.0) | 7.5 (1.1 to 13.9) | 12.7 (6.6 to 18.8) | 14.8 (5.2 to 24.4) | |
| HF | |||||||
| N events | 329 | 212 | 76 | 51 | 84 | 60 | |
| Age 55 | 10 years | 23.2 (20.3 to 26.1) | 24.2 (20.9 to 27.5) | 23.8 (18.0 to 29.6) | 29.5 (22.9 to 36.1) | 35.0 (28.4 to 41.6) | 32.9 (26.8 to 39.0) |
| Lifetime | 26.9 (24.0 to 29.9) | 30.3 (26.7 to 33.9) | 32.6 (26.4 to 38.9) | 31.8 (25.2 to 38.5) | 35.1 (28.6 to 41.6) | 31.2 (25.2 to 37.2) | |
| Age 65 | 10 years | 22.9 (20.0 to 25.9) | 23.2 (19.8 to 26.6) | 23.1 (17.3 to 28.9) | 28.5 (21.9 to 35.2) | 32.9 (26.8 to 39.0) | 31.3 (25.4 to 37.3) |
| Lifetime | 27.2 (24.2 to 30.2) | 29.8 (26.1 to 33.6) | 32.3 (26.0 to 38.7) | 31.0 (24.3 to 37.7) | 33.5 (27.4 to 39.6) | 30.3 (24.4 to 36.2) | |
| Age 75 | 10 years | 22.0 (18.8 to 25.2) | 20.6 (16.8 to 24.4) | 22.0 (15.6 to 28.4) | 26.8 (19.3 to 34.2) | 27.3 (21.2 to 33.4) | 30.0 (23.3 to 36.8) |
| Lifetime | 27.3 (24.0 to 30.6) | 28.3 (24.1 to 32.6) | 32.5 (25.3 to 39.7) | 31.1 (23.6 to 38.7) | 29.5 (23.4 to 35.6) | 30.5 (23.8 to 37.2) | |
| Age 85 | 10 years | 18.8 (14.8 to 22.8) | 18.8 (12.9 to 24.7) | 14.8 (7.5 to 22.1) | 22.5 (11.1 to 33.8) | 18.3 (11.0 to 25.6) | 19.9 (10.4 to 29.5) |
| Lifetime | 23.4 (19.3 to 27.6) | 28.9 (22.1 to 35.8) | 29.0 (20.1 to 37.8) | 28.2 (16.6 to 39.8) | 24.2 (16.5 to 31.9) | 21.7 (12.0 to 31.4) | |
| Stroke | |||||||
| N events | 322 | 213 | 64 | 52 | 88 | 65 | |
| Age 55 | 10 years | 22.7 (20.0 to 25.5) | 22.2 (18.8 to 25.5) | 23.9 (18.2 to 29.7) | 24.8 (18.3 to 31.2) | 37.6 (30.1 to 45.2) | 30.7 (24.4 to 37.1) |
| Lifetime | 25.5 (22.8 to 28.2) | 24.9 (21.5 to 28.3) | 27.5 (21.5 to 33.5) | 28.2 (21.6 to 34.8) | 33.1 (26.4 to 39.8) | 28.7 (22.5 to 34.9) | |
| Age 65 | 10 years | 22.1 (19.4 to 24.5) | 20.6 (17.1 to 24.1) | 24.5 (18.6 to 30.4) | 22.4 (16.5 to 28.3) | 33.2 (27.1 to 39.4) | 24.0 (18.6 to 29.5) |
| Lifetime | 25.3 (22.6 to 28.1) | 24.2 (20.7 to 27.6) | 28.1 (22.0 to 34.2) | 26.1 (20.0 to 32.3) | 31.7 (25.6 to 37.8) | 23.0 (17.6 to 28.4) | |
| Age 75 | 10 years | 20.7 (17.7 to 23.6) | 16.7 (12.7 to 20.6) | 20.7 (14.4 to 27.0) | 19.7 (13.2 to 26.2) | 30.8 (24.6 to 37.1) | 20.9 (14.9 to 26.8) |
| Lifetime | 24.0 (21.1 to 27.0) | 21.1 (17.1 to 25.0) | 24.8 (18.1 to 31.5) | 22.4 (15.6 to 29.3) | 29.0 (22.8 to 35.2) | 21.6 (15.6 to 27.7) | |
| Age 85 | 10 years | 17.3 (13.7 to 20.8) | 14.7 (8.5 to 20.9) | 17.2 (9. to 24.5) | 12.3 (3.6 to 21.1) | 24.8 (16.9 to 32.7) | 20.2 (10.6 to 29.8) |
| Lifetime | 18.5 (15.0 to 22.0) | 19.9 (13.8 to 26.1) | 22.9 (14.9 to 30.9) | 16.7 (7.1 to 26.4) | 22.8 (15.1 to 30.6) | 21.2 (11.2 to 31.1) | |
CHD, coronary heart disease; CVD, cardiovascular disease; HF, heart failure.