Table 2

Remaining lifetime risks vs 10-year risks of first incident cardiovascular disease by glycemic status among women and men

NormoglycemiaImpaired fasting glucoseType 2 diabetes
Cumulative incidence, % (95% CI)Cumulative incidence, % (95% CI)Cumulative incidence, % (95% CI)
Women (n=4468)Men (n=2753)Women (n=634)Men (n=570)Women (n=596)Men (n=480)
CVD
N events740608149147182155
Age 5510 years47.7 (44.3 to 51.1)53.9 (50.1 to 57.7)47.2 (39.9 to 54.4)56.5 (49.0 to 64.0)65.3 (58.6 to 72.1)63.8 (56.9 to 70.7)
Lifetime52.7 (49.5 to 55.9)59.1 (55.5 to 62.7)55.1 (48.3 to 61.9)62.1 (55.2 to 69.1)61.5 (54.7 to 68.3)60.3 (53.1 to 67.5)
Age 6510 years46.6 (43.1 to 50.1)47.5 (43.3 to 51.8)45.9 (38.5 to 53.3)52.5 (44.6 to 60.4)63.7 (57.3 to 70.1)57.5 (50.1 to 64.9)
Lifetime52.4 (49.2 to 55.7)55.5 (51.7 to 59.4)49.9 (48.1 to 61.8)59.4 (52.1 to 66.7)61.4 (54.8 to 67.9)56.4 (48.9 to 63.9)
Age 7510 years43.2 (39.2 to 47.2)39.7 (34.4 to 45.0)43.0 (34.3 to 51.7)46.9 (37.0 to 56.7)58.8 (51.7 to 66.0)50.2 (41.0 to 59.3)
Lifetime50.8 (47.1 to 54.5)51.3 (46.5 to 56.0)53.6 (45.5 to 61.7)56.0 (47.0 to 65.1)58.1 (50.9 to 65.4)51.1 (42.0 to 60.3)
Age 8510 years37.4 (32.1 to 42.7)32.8 (23.7 to 41.8)34.2 (22.9 to 45.4)36.6 (20.0 to 53.2)45.9 (35.3 to 56.5)44.9 (29.0 to 60.8)
Lifetime43.9 (38.8 to 49.0)48.1 (39.9 to 56.3)49.7 (39.3 to 60.2)46.0 (29.7 to 62.4)47.9 (37.5 to 58.4)45.6 (29.0 to 62.2)
CHD
N events23832850656470
Age 5510 years16.8 (14.4 to 19.2)29.3 (26.2 to 32.5)15.1 (10.4 to 19.7)25.9 (19.4 to 32.3)28.7 (22.2 to 35.1)34.7 (27.8 to 41.6)
Lifetime18.8 (16.4 to 21.2)33.3 (29.9 to 36.6)18.0 (12.8 to 23.1)30.2 (23.7 to 36.6)24.0 (18.0 to 30.2)30.9 (24.2 to 37.6)
Age 6510 years15.5 (13.1 to 17.9)21.1 (18.2 to 24.1)13.4 (9.1 to 17.8)18.9 (13.3 to 24.6)25.0 (19.3 to 30.8)27.9 (21.6 to 34.3)
Lifetime18.0 (15.6 to 20.4)27.5 (24.2 to 30.8)17.6 (12.5 to 22.7)24.6 (18.7 to 30.6)21.0 (15.6 to 26.4)27.1 (20.7 to 33.4)
Age 7510 years12.5 (10.0 to 15.0)13.1 (10.1 to 16.0)10.4 (6.2 to 14.7)11.3 (5.8 to 16.9)19.2 (13.8 to 24.6)20.8 (14.3 to 27.4)
Lifetime15.7 (13.2 to 18.3)21.2 (17.5 to 24.8)14.3 (9.0 to 19.6)18.9 (12.6 to 25.1)18.0 (12.7 to 23.3)22.2 (15.5 to 29.0)
Age 8510 years9.9 (7.0 to 12.9)8.0 (4.1 to 12.0)3.2 (0.1 to 6.3)6.9 (0.3 to 13.5)12.6 (6.6 to 18.6)10.4 (2.4 to 18.3)
Lifetime11.8 (8.9 to 14.8)16.1 (10.8 to 21.5)11.1 (5.1 to 17.0)7.5 (1.1 to 13.9)12.7 (6.6 to 18.8)14.8 (5.2 to 24.4)
HF
N events32921276518460
Age 5510 years23.2 (20.3 to 26.1)24.2 (20.9 to 27.5)23.8 (18.0 to 29.6)29.5 (22.9 to 36.1)35.0 (28.4 to 41.6)32.9 (26.8 to 39.0)
Lifetime26.9 (24.0 to 29.9)30.3 (26.7 to 33.9)32.6 (26.4 to 38.9)31.8 (25.2 to 38.5)35.1 (28.6 to 41.6)31.2 (25.2 to 37.2)
Age 6510 years22.9 (20.0 to 25.9)23.2 (19.8 to 26.6)23.1 (17.3 to 28.9)28.5 (21.9 to 35.2)32.9 (26.8 to 39.0)31.3 (25.4 to 37.3)
Lifetime27.2 (24.2 to 30.2)29.8 (26.1 to 33.6)32.3 (26.0 to 38.7)31.0 (24.3 to 37.7)33.5 (27.4 to 39.6)30.3 (24.4 to 36.2)
Age 7510 years22.0 (18.8 to 25.2)20.6 (16.8 to 24.4)22.0 (15.6 to 28.4)26.8 (19.3 to 34.2)27.3 (21.2 to 33.4)30.0 (23.3 to 36.8)
Lifetime27.3 (24.0 to 30.6)28.3 (24.1 to 32.6)32.5 (25.3 to 39.7)31.1 (23.6 to 38.7)29.5 (23.4 to 35.6)30.5 (23.8 to 37.2)
Age 8510 years18.8 (14.8 to 22.8)18.8 (12.9 to 24.7)14.8 (7.5 to 22.1)22.5 (11.1 to 33.8)18.3 (11.0 to 25.6)19.9 (10.4 to 29.5)
Lifetime23.4 (19.3 to 27.6)28.9 (22.1 to 35.8)29.0 (20.1 to 37.8)28.2 (16.6 to 39.8)24.2 (16.5 to 31.9)21.7 (12.0 to 31.4)
Stroke
N events32221364528865
Age 5510 years22.7 (20.0 to 25.5)22.2 (18.8 to 25.5)23.9 (18.2 to 29.7)24.8 (18.3 to 31.2)37.6 (30.1 to 45.2)30.7 (24.4 to 37.1)
Lifetime25.5 (22.8 to 28.2)24.9 (21.5 to 28.3)27.5 (21.5 to 33.5)28.2 (21.6 to 34.8)33.1 (26.4 to 39.8)28.7 (22.5 to 34.9)
Age 6510 years22.1 (19.4 to 24.5)20.6 (17.1 to 24.1)24.5 (18.6 to 30.4)22.4 (16.5 to 28.3)33.2 (27.1 to 39.4)24.0 (18.6 to 29.5)
Lifetime25.3 (22.6 to 28.1)24.2 (20.7 to 27.6)28.1 (22.0 to 34.2)26.1 (20.0 to 32.3)31.7 (25.6 to 37.8)23.0 (17.6 to 28.4)
Age 7510 years20.7 (17.7 to 23.6)16.7 (12.7 to 20.6)20.7 (14.4 to 27.0)19.7 (13.2 to 26.2)30.8 (24.6 to 37.1)20.9 (14.9 to 26.8)
Lifetime24.0 (21.1 to 27.0)21.1 (17.1 to 25.0)24.8 (18.1 to 31.5)22.4 (15.6 to 29.3)29.0 (22.8 to 35.2)21.6 (15.6 to 27.7)
Age 8510 years17.3 (13.7 to 20.8)14.7 (8.5 to 20.9)17.2 (9. to 24.5)12.3 (3.6 to 21.1)24.8 (16.9 to 32.7)20.2 (10.6 to 29.8)
Lifetime18.5 (15.0 to 22.0)19.9 (13.8 to 26.1)22.9 (14.9 to 30.9)16.7 (7.1 to 26.4)22.8 (15.1 to 30.6)21.2 (11.2 to 31.1)
  • CHD, coronary heart disease; CVD, cardiovascular disease; HF, heart failure.