Table 1

Baseline characteristics by baseline body mass index (BMI) subgroup

CharacteristicBMI <25 kg/m2BMI 25–<30 kg/m2BMI ≥30 kg/m2P value*
PBO
(n=79)
LIXI
(n=104)
Total
(n=183)
PBO
(n=142)
LIXI
(n=134)
Total
(n=276)
PBO
(n=42)
LIXI
(n=54)
Total
(n=96)
Age, years56.0±9.954.3±9.955.0±9.955.1±9.153.4±9.454.3±9.350.2±7.751.2±10.550.8±9.40.001
Male, n (%)40 (50.6)51 (49.0)91 (49.7)76 (53.5)83 (61.9)159 (57.6)23 (54.8)18 (33.3)41 (42.7)0.028
HbA1c, %7.9±0.78.0±0.78.0±0.78.0±0.78.0±0.88.0±0.88.1±0.88.0±0.88.1±0.80.559
Duration of diabetes, years10.6±6.111.2±6.611.0±6.410.4±6.310.0±6.010.2±6.18.6±6.69.2±6.59.0±6.60.044
Duration of basal insulin, years†2.3±2.42.5±3.02.4±2.82.5±2.72.0±2.42.3±2.51.7±1.72.3±2.62.1±2.20.577
FPG, mmol/L6.8±1.87.1±2.37.0±2.16.7±1.87.1±2.26.9±2.07.1±2.16.9±1.77.0±1.90.921
2-hour PPG, mmol/L14.1±3.414.7±4.914.4±4.314.2±3.913.9±4.214.1±4.014.1±3.812.9±3.813.4±3.80.143
Basal insulin dose, U/day30.7±11.633.3±13.532.2±12.738.1±15.137.4±16.237.8±15.652.2±31.450.1±22.451.0±26.6<0.001
Basal insulin dose, U/day/kg0.5±0.20.6±0.20.5±0.20.5±0.20.5±0.20.5±0.20.6±0.30.6±0.30.6±0.30.154
BMI, kg/m223.0±1.323.2±1.323.2±1.327.4±1.527.1±1.427.2±1.533.4±2.532.9±2.533.1±2.5
Body weight, kg61.9±7.461.6±7.461.7±7.473.0±9.973.5±9.773.2±9.889.4±10.585.3±11.887.1±11.4
  • All values are given as mean±SD unless otherwise stated.

  • *P value for differences between total participants of the different BMI subgroups.

  • †Only available for GetGoal-L and GetGoal-L-C Studies.

  • FPG, fasting plasma glucose; HbA1c, glycated hemoglobin; LIXI, lixisenatide; PBO, placebo; PPG, postprandial glucose.