Table 4

Summary of multivariable regression results of the association of body mass index (BMI) subgroup with different clinical responses in Asian participants with type 2 diabetes

BMI <25 vs ≥30 kg/m2BMI 25–<30 vs ≥30 kg/m2
Estimated difference
(95% CI)
P valueEstimated difference
(95% CI)
P value
Change in HbA1c, %0.18 (–0.09 to 0.44)0.187–0.02 (–0.27 to 0.22)0.857
Change in FPG, mmol/L–0.26 (–0.83 to 0.30)0.360–0.23 (–0.76 to 0.31)0.402
Change in 2-hour PPG, mmol/L0.47 (–0.74 to 1.67)0.4480.10 (–1.04 to 1.24)0.861
Change in body weight, kg0.68 (0.09 to 1.26)0.0230.13 (–0.42 to 0.67)0.654
Change in basal insulin dose, U/day0.48 (–1.20 to 2.15)0.5760.14 (–1.43 to 1.71)0.858
Endpoint basal insulin dose, U/day–13.95 (–16.14 to 11.76)<0.001–9.41 (–11.46 to 7.35)<0.001
Change in basal insulin dose, U/kg/day0.007 (–0.018 to 0.032)0.5930.005 (–0.018 to 0.029)0.645
Endpoint basal insulin dose, U/kg/day0.007 (–0.018 to 0.032)0.5930.005 (–0.018 to 0.029)0.645
OR (95% CI)P valueOR (95% CI)P value
Endpoint HbA1c <7%0.97 (0.48 to 1.93)0.6911.15 (0.60 to 2.21)0.519
Endpoint HbA1c <7% and no body weight gain0.40 (0.18 to 0.90)0.0051.02 (0.50 to 2.07)0.089
  • FPG, fasting plasma glucose; HbA1c, glycated hemoglobin; PPG, postprandial glucose.