Table 2

MRI results

MetricNROIBaseline1Baseline2PbaseΔbase (%)PostP valueΔpost (%)
FF (%)19Interior10.8±3.410.8±3.70.9320.3±8.410.5±3.30.097−2.6±6.4
19GM8.6±4.68.5±4.00.7331.7±11.38.4±4.00.564−1.8±8.7
19GL7.4±4.07.6±3.80.4023.9±11.67.5±3.90.520−2.5±12.0
19SOL9.9±4.09.8±4.10.718−0.5±7.79.9±4.20.8550.0±9.5
τ(s)15GM+GL34.1±20.635.4±21.80.5517.4±27.432.3±21.70.309−4.6±30.2
FA17TN0.34±0.060.32±0.070.319−4.2±20.60.33±0.050.6944.2±17.7
ADC (x103 mm2/s)17TN1.77±0.311.76±0.200.9222.0±20.41.81±0.190.4633.9±16.6
T1 (ms)12GM940.9±43.3918.3±20.00.023−2.3±3.0
12GL947.5±42.4935.0±18.70.274−1.2±3.8
12SOL938.3±34.4935.7±23.60.727−0.2±2.7
T1ρ (ms)12GM31.0±3.729.6±1.80.078−4.1±7.7
12GL30.0±4.529.1±2.00.365−1.8±10.6
12SOL31.7±3.031.6±2.80.9740.2±7.3
T2 (ms)12GM25.3±2.624.2±1.20.095−3.5±6.4
12GL26.6±2.725.2±1.80.055−4.6±7.4
12SOL23.9±1.323.1±1.40.003−3.2±3.1
  • Pbase indicates statistical differences between baseline1 and baseline2 values (paired, two-tailed Student’s t-test). P indicates differences between baseline2 and postintervention values. P values in bold type indicate statistically significant differences or trends toward significance (p<0.1).

  • ADC, apparent diffusion coefficient; Δbase, percentage change between baseline1 and baseline2 values; FA, fractional anisotropy; FF, fat fraction; GL, gastrocnemius lateralis; GM, gastrocnemius medialis; Δpost, percentage change between baseline2 and postintervention values; post, postintervention; ROI, region of interest; SOL, soleus; TN, tibial nerve.