Table 1

Baseline characteristics by glucose response curve shape

AllMonophasicBiphasicContinuous riseOverall p valueM vs BM vs CB vs C
P valueP valueP value
n31082107172829
Female (%)1124 (36.2)645 (30.6)71 (41.3)408 (49.2)<0.0010.005<0.0010.070
Age (years)56.6 (10.0)56.0 (9.9)57.0 (10.9)58.1 (9.9)<0.0010.216<0.0010.249
Age (years) (%)<0.0010.048<0.0010.242
 22–50835 (26.9)602 (28.6)49 (28.5)184 (22.2)
 >50–601095 (35.2)757 (35.9)49 (28.5)289 (34.9)
 >60–70970 (31.2)637 (30.2)58 (33.7)275 (33.2)
 >70–85207 (6.7)110 (5.2)16 (9.3)81 (9.8)
Race (%)<0.0010.080<0.0010.139
 American Indian/Alaska Native103 (3.3)73 (3.5)8 (4.7)22 (2.7)
 Asian119 (3.8)75 (3.6)13 (7.6)31 (3.7)
 Hawaiian/Pacific Islander20 (0.6)17 (0.8)1 (0.6)2 (0.2)
 African American/black553 (17.8)330 (15.7)34 (19.8)189 (22.8)
 White2084 (67.1)1466 (69.6)107 (62.2)515 (62.1)
 Other/multiple189 (6.1)121 (5.7)8 (4.7)60 (7.2)
 Unknown/not reported40 (1.3)29 (1.4)1 (0.6)10 (1.2)
Hispanic (%)611 (19.8)391 (18.7)34 (19.9)186 (22.7)0.0530.7800.0180.484
Anthropometrics
Weight (kg)99.6 (22.1)103.2 (22.4)93.6 (21.8)91.4 (19.0)<0.001<0.001<0.0010.216
BMI (kg/m2)34.2 (6.7)34.9 (6.8)32.5 (6.4)32.5 (6.0)<0.001<0.001<0.0010.904
Waist circumference (cm)112.2 (15.7)114.4 (15.6)108.8 (18.1)107.3 (14.3)<0.001<0.001<0.0010.306
Duration of diabetes (years)4.0 (2.8)3.9 (2.7)4.3 (2.8)4.3 (2.8)0.0060.1080.0040.907
Metformin dose (mg/day) (%)0.0010.040<0.0010.478
 1000107 (3.4)60 (2.8)6 (3.5)41 (4.9)
 1500125 (4.0)70 (3.3)12 (7.0)43 (5.2)
 20002876 (92.5)1977 (93.8)154 (89.5)745 (89.9)
eGFR (mL/min/1.73 m2)95.4 (16.9)95.7 (16.6)95.8 (7.6)94.8 (17.4)0.4140.9130.2040.478
  • Mean (SD).

  • B, biphasic shape; BMI, body mass index; C, continuous rise shape; eGFR, estimated glomerular filtration rate; M, monophasic shape.