Table 1

Descriptive data including autoantibodies of study participants at baseline

ParameterSubjects (n=6)
Male (%)100
Age (years)24.8±1.5
Age at onset (years)10.3±2.2
T1D duration (years)14.7±2.2
BMI (kg/m2, ref: 20–25)22.6±1.4
Hemoglobin (g/L, ref: 130–170)142.8±3.1
Creatinine (µmol/L, ref: 60–105)74.2±2.2
Bilirubin (µmol/L, ref: 5–25)14.4±2.0
ALT (µkat/L, ref: 0.15–1.1)0.37±0.08
AST (µkat/L, ref: 0.25–0.75)0.43±0.09
ALP (µkat/L, ref: 0.6–1.8)1.4±0.1
HbA1c (mmol/mol, ref: 27–42)64.8±6.2
Fasting C peptide >0.01 nmol/L (n)1
GAD positive (n)3
IA2 positive (n)4
  • Reference values are presented within brackets.

  • The cut-off for positive GAD autoantibodies was set to >5 IE/mL and for IA2 to >7.5 kE/L according to clinical routine.

  • ALP, alkaline phosphate; ALT, alanine aminotransferase; AST, aspartate transaminase; BMI, body mass index; GAD, glutamic acid decarboxylase; HbA1c, hemoglobin A1c; IA2, Islet Antigen 2; ref, reference; T1D, type 1 diabetes.