Table 2

Multiple stepwise linear regression analysis of factors associated with the SMI and MMA

VariableBeta (95% CI)P value
Male9.06 (7.18 to 10.95)<0.001
BMI1.00 (0.75 to 1.26)<0.001
Age−0.10 (−0.18 to 0.02)0.012
Cre/CysC0.48 (0.02 to 0.94)0.042
Male3.68 (1.89 to 5.47)<0.001
BMI−0.48 (−0.72 to to 0.24)<0.001
Age−0.21 (−0.28 to 0.13)<0.001
Cre/CysC0.57 (0.14 to 1.01)0.011
  • Adopted factors: sex, age, BMI, WHR, Cre/CysC, creatinine, albumin, high-density lipoproteins, HOMA2 %B, HOMA2 %S, fasting blood glucose and fasting C peptide for the SMI; sex, age, duration, BMI, WHR, Cre/CysC, cystatin C, albumin, triglycerides, high-density lipoproteins, low-density lipoproteins, hypertension, cardiovascular disease and diabetic nephropathy for the MMA. R2=0.788 for the SMI and 0.612 for the MMA.

  • BMI, body mass index; Cre/CysC, creatinine-to-cystatin C ratio; HOMA2, homeostasis model assessment; MMA, mean skeletal muscle attenuation; SMI, skeletal muscle index; WHR, waist–hip ratio.