Table 3

Results from Cox regression models for T2DM− versus T2DM+

HR unadjustedP valueHR adjusted*P value
3-point MACE1.78 (1.44 to 2.19)<0.0011.44 (1.09 to 1.92)0.012
Vascular mortality2.17 (1.62 to 2.91)<0.0011.73 (1.15 to 2.60)0.008
Stroke1.65 (1.13 to 2.40)0.0091.20 (0.72 to 2.02)0.489
MCI1.46 (1.03 to 2.06)0.0341.27 (0.80 to 2.02)0.308
All-cause mortality1.70 (1.42 to 2.03)<0.0011.29 (1.00 to 1.65)0.050
  • *Adjustments were made for age, gender, BMI, history of smoking, arterial hypertension, systolic blood pressure, LDL cholesterol, HDL cholesterol, HbA1c, eGFR, use of statins, ACE inhibitors/ATII RBA and aspirin/clopidogrel.

  • ACE, angiotensin converting enzyme; ATII RBA, ATII receptor blocking agents; BMI, body mass index; eGFR, estimated glomerular filtration rate; HbA1c, hemoglobin A1c; HDL, high density lipoprotein; LDL, low density lipoprotein; MCI, myocardial infarction; 3-point MACE, major cardiovascular endpoint (including cardiovascular death, non-fatal myocardial infarction and non-fatal stroke); T2DM, type 2 diabetes mellitus.