Baseline characteristics
CAD | P value | PAD | P value | |||
T2DM− | T2DM+ | T2DM− | T2DM+ | |||
n=677 | n=246 | n=169 | n=123 | |||
Age (years) | 64.4±10.4 | 64.9±10.2 | 0.658 | 65.4±9.3 | 66.7±9.9 | 0.442 |
Male gender (%) | 70.2 | 69.9 | 0.943 | 68.0 | 74.8% | 0.210 |
Diabetes duration (years) | 5.0±7.0 | 7.1±8.7 | ||||
Hypertension (%) | 80.1 | 85.4 | 0.067 | 91.7 | 92.7 | 0.762 |
Smoking (%) | 56.1 | 61.8 | 0.124 | 82.8 | 82.1 | 0.872 |
Body mass index (kg/m2) | 27.0±3.9 | 28.8±4.5 | <0.001 | 26.2±4.3 | 28.3±4.9 | <0.001 |
Waist circumference (cm) | 96±11 | 102±11 | <0.001 | 96±13 | 103±14 | <0.001 |
HbA1c (%) | 5.7±0.3 | 7.2±1.3 | <0.001 | 5.6±0.3 | 7.2±1.5 | <0.001 |
Triglycerides (mg/dL) | 139±90 | 175±103 | <0.001 | 135±78 | 162±100 | 0.180 |
Total cholesterol (mg/dL) | 213±46 | 204±47 | 0.005 | 192±39 | 182±52 | 0.160 |
LDL cholesterol (mg/dL) | 137±40 | 126±39 | <0.001 | 119±36 | 111±44 | 0.240 |
HDL cholesterol (mg/dL) | 55±16 | 49±14 | <0.001 | 57±18 | 48±15 | <0.001 |
Apolipoprotein A1 (mg/dL) | 154±28 | 147±27 | 0.001 | 163±33 | 148±34 | <0.001 |
Apolipoprotein B (mg/dL) | 99±29 | 100±30 | 0.476 | 82±21 | 84±29 | 0.934 |
Systolic blood pressure (mm Hg) | 137±19 | 139±20 | 0.346 | 141±22 | 143±25 | 0.421 |
Diastolic blood pressure (mm Hg) | 81±10 | 81±12 | 0.638 | 80±11 | 81±14 | 0.898 |
Statins (%) | 42.2 | 43.5 | 0.734 | 60.9 | 65.9 | 0.391 |
ACE inhibitors/ATII RBA (%) | 36.8 | 47.6 | 0.003 | 45.6 | 61.8 | 0.006 |
Beta receptor blocking agents (%) | 50.7 | 46.3 | 0.245 | 34.9 | 43.1 | 0.156 |
Aspirin or clopidogrel (%) | 66.1 | 69.1 | 0.387 | 82.8 | 83.7 | 0.839 |
To convert values for fasting plasma glucose to mmol/L multiply by 0.0555, to convert values for triglycerides to mmol/L multiply by 0.0113 and to convert values for total cholesterol, LDL cholesterol or HDL cholesterol to mmol/L multiply by 0.0259. Data are shown as means±SD if not denoted otherwise.
ACE, angiotensin converting enzyme; ATII RBA, angiotensin II receptor blocking agents; CAD, coronary artery disease; HbA1c, hemoglobin A1c; HDL, high density lipoprotein; LDL, low density lipoprotein; PAD, peripheral artery disease; T2DM, type 2 diabetes mellitus.