Table 3

Logistic regression analysis for predictors of hospital utilization for hypoglycemia in 2014

Characteristic	n (%) (n=290 075)	OR (95% CI) Model 1*	P value	OR (95% CI) Model 2*	P value
Age category (years)			<0.001		<0.001
18–39	16 628 (5.7)	2.22 (1.69 to 3.03)		2.43 (1.78 to 3.31)
40–64	137 133 (47.3)	Reference		Reference
65–74	74 940 (25.8)	0.84 (0.65 to 1.10)		0.74 (0.57 to 0.97)
≥75	61 374 (21.2)	0.99 (0.76 to 1.30)		0.74 (0.56 to 0.99)
Female sex (reference: Male)	152 269 (52.5)	1.32 (1.08 to 1.61)	0.007	1.43 (1.16 to 1.75)	<0.001
Race/ethnicity			<0.001		<0.001
White, non-Hispanic	221 863 (76.5)	Reference		Reference
Black, non-Hispanic	43 971 (15.2)	2.16 (1.67 to 2.78)		1.84 (1.43 to 2.38)
Other, non-Hispanic	7663 (2.6)	1.09 (0.55 to 2.15)		1.20 (0.61 to 2.37)
Hispanic	13 344 (4.6)	1.67 (0.97 to 2.86)		1.59 (0.93 to 2.71)
Missing	3234 (1.1)	0.34 (0.48 to 2.44)		0.35 (0.05 to 2.50)
Diabetes medication category			<0.001		<0.001
No medication	149 203 (51.4)	Reference		Reference
Low-risk medication	55 505 (19.1)	0.40 (0.27 to 0.60)		0.44 (0.29 to 0.67
High-risk oral medication†	34 647 (11.9)	0.83 (0.57 to 1.22)		0.83 (0.56 to 1.23)
Insulin	50 720 (17.5)	2.68 (2.15 to 3.33)		2.13 (1.67 to 2.73)
Chronic kidney disease	64 436 (22.2)	3.68 (3.00 to 4.52)	<0.001	2.86 (2.33 to 3.57)	<0.001
Cognitive impairment	14 751 (5.1)	2.57 (1.85 to 3.56)	<0.001	1.92 (1.39 to 2.70)	<0.001
HbA1c category			<0.001		<0.001
<6.0%	23 491 (8.1)	2.30 (1.55 to 3.42)		2.00 (1.33 to 2.94)
6.0%–6.9%	59 293 (20.4)	Reference		Reference
7.0%–7.9%	35 571 (12.3)	1.71 (1.16 to 2.52)		1.39 (0.94 to 2.08)
8.0%–8.9%	17 883 (6.2)	1.85 (1.16 to 2.93)		1.20 (0.75 to 1.92)
≥9.0%	24 616 (8.5)	2.69 (1.84 to 3.92)		1.56 (1.05 to 2.33)
Missing	129 221 (44.6)	1.38 (1.01 to 1.90)		1.33 (0.97 to 1.85)

*Model 1 adjusted for age, sex, race/ethnicity and study site. Model 2 adjusted for model 1+diabetes medication category, chronic kidney disease, cognitive impairment, and HbA1c category.
†Sulfonylurea or meglitinide.
HbA1c, hemoglobin A1c.