Table 4

Multiple logistic regression with advanced diabetic nephropathy as the dependent variable

Model 1Model 2Model 3Model 4
OR95% CIP valueOR95% CIP valueOR95% CIP valueOR95% CIP value
Sex2.231.12 to 4.610.0262.231.11 to 4.510.0252.281.12 to 4.650.0232.351.15 to 4.820.019
Duration1.051.02 to 1.080.00231.051.02 to 1.080.00191.051.02 to 1.080.00221.041.00 to 1.070.039
HbA1c1.251.07 to 1.470.00671.241.06 to 1.470.00831.191.01 to 1.410.0371.211.03 to 1.430.025
CPI1.511.07 to 2.140.0201.430.99 to 2.090.0561.220.83 to 1.780.301.250.84 to 1.820.26
HT5.872.68 to 14.44<0.00015.682.46 to 13.13<0.00015.532.39 to 12.81<0.00014.972.13 to 11.620.0002
HUA3.311.77 to 6.210.00023.241.73 to 6.080.00023.381.79 to 6.390.00023.351.76 to 6.360.0002
BMI1.020.96 to 1.090.46
MBBO1.091.03 to 1.150.00181.101.04 to 1.160.0009
Δyear1.020.99 to 1.050.10
AUC: 0.812AUC: 0.812AUC: 0.828AUC: 0.831
  • Model 1: All explanatory variables except BMI on admission, MBBO, and age at MBBO were included and then excluded if the variable was not statistically significant at a 20% level (p<0.20) via stepwise backward elimination. Model 2: model 1+BMI on admission; model 3: model 1+MBBO; model 4: model 3+Δyear.

  • AUC, area under the curve; BMI, BMI on admission; CPI, C-peptide index; HbA1c, hemoglobin A1c; HT, hypertension; HUA, hyperuricemia; MBBO, maximum BMI before onset; Δyear, the period from age at MBBO to admission.