Multiple logistic regression with advanced diabetic nephropathy as the dependent variable
| Model 1 | Model 2 | Model 3 | Model 4 | |||||||||
| OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | |
| Sex | 2.23 | 1.12 to 4.61 | 0.026 | 2.23 | 1.11 to 4.51 | 0.025 | 2.28 | 1.12 to 4.65 | 0.023 | 2.35 | 1.15 to 4.82 | 0.019 |
| Duration | 1.05 | 1.02 to 1.08 | 0.0023 | 1.05 | 1.02 to 1.08 | 0.0019 | 1.05 | 1.02 to 1.08 | 0.0022 | 1.04 | 1.00 to 1.07 | 0.039 |
| HbA1c | 1.25 | 1.07 to 1.47 | 0.0067 | 1.24 | 1.06 to 1.47 | 0.0083 | 1.19 | 1.01 to 1.41 | 0.037 | 1.21 | 1.03 to 1.43 | 0.025 |
| CPI | 1.51 | 1.07 to 2.14 | 0.020 | 1.43 | 0.99 to 2.09 | 0.056 | 1.22 | 0.83 to 1.78 | 0.30 | 1.25 | 0.84 to 1.82 | 0.26 |
| HT | 5.87 | 2.68 to 14.44 | <0.0001 | 5.68 | 2.46 to 13.13 | <0.0001 | 5.53 | 2.39 to 12.81 | <0.0001 | 4.97 | 2.13 to 11.62 | 0.0002 |
| HUA | 3.31 | 1.77 to 6.21 | 0.0002 | 3.24 | 1.73 to 6.08 | 0.0002 | 3.38 | 1.79 to 6.39 | 0.0002 | 3.35 | 1.76 to 6.36 | 0.0002 |
| BMI | 1.02 | 0.96 to 1.09 | 0.46 | |||||||||
| MBBO | 1.09 | 1.03 to 1.15 | 0.0018 | 1.10 | 1.04 to 1.16 | 0.0009 | ||||||
| Δyear | 1.02 | 0.99 to 1.05 | 0.10 | |||||||||
| AUC: 0.812 | AUC: 0.812 | AUC: 0.828 | AUC: 0.831 | |||||||||
Model 1: All explanatory variables except BMI on admission, MBBO, and age at MBBO were included and then excluded if the variable was not statistically significant at a 20% level (p<0.20) via stepwise backward elimination. Model 2: model 1+BMI on admission; model 3: model 1+MBBO; model 4: model 3+Δyear.
AUC, area under the curve; BMI, BMI on admission; CPI, C-peptide index; HbA1c, hemoglobin A1c; HT, hypertension; HUA, hyperuricemia; MBBO, maximum BMI before onset; Δyear, the period from age at MBBO to admission.